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    CadN Cadherin-N [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 657652, updated on 6-Jun-2024

    Summary

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    Gene symbol
    CadN
    Gene description
    Cadherin-N
    Locus tag
    TcasGA2_TC013220
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Orthologs
    fruit fly all
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    Genomic context

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    See CadN in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 5 NC_087398.1 (3721097..3893003)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Linkage Group LG5 NC_007420.3 (11913933..12086308, complement)

    Chromosome 5 - NC_087398.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene cilia- and flagella-associated protein 20 Neighboring gene cGMP-dependent protein kinase, isozyme 1 Neighboring gene proteasome subunit alpha type-7-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adherens junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion mediated by cadherin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catenin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neural-cadherin
    Names
    AUGUSTUS-3.0.2_13220
    AUGUSTUS-3.0.2_33193
    DN cadherin-like protein
    GLEAN_13220
    GLEAN_13221
    GLEAN_13225
    GLEAN_13226
    GLEAN_13227
    Neural-cadherin-like Protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087398.1 Reference icTriCast1.1 Primary Assembly

      Range
      3721097..3893003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008195795.3 → XP_008194017.1  neural-cadherin isoform X2

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (7) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:2790 → 2828
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2873 → 3004
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    2. XM_008195801.3 → XP_008194023.1  neural-cadherin isoform X6

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (8) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00181
      Location:2747 → 2787
      EGF; Epidermal growth factor-like domain
      cd00054
      Location:2788 → 2826
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2872 → 3003
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    3. XM_008195794.3 → XP_008194016.1  neural-cadherin isoform X4

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (7) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:2790 → 2828
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2873 → 3004
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    4. XM_008195798.3 → XP_008194020.1  neural-cadherin isoform X8

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (8) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00181
      Location:2747 → 2787
      EGF; Epidermal growth factor-like domain
      cd00054
      Location:2788 → 2826
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2872 → 3003
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    5. XM_008195797.3 → XP_008194019.1  neural-cadherin isoform X1

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (7) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:2790 → 2828
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2873 → 3004
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    6. XM_008195802.3 → XP_008194024.1  neural-cadherin isoform X5

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (8) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00181
      Location:2747 → 2787
      EGF; Epidermal growth factor-like domain
      cd00054
      Location:2788 → 2826
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2872 → 3003
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    7. XM_008195796.3 → XP_008194018.1  neural-cadherin isoform X3

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (7) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:2790 → 2828
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2873 → 3004
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    8. XM_008195800.3 → XP_008194022.1  neural-cadherin isoform X7

      UniProtKB/TrEMBL
      A0A139WH45
      Conserved Domains (8) summary
      cd11304
      Location:897 → 998
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00181
      Location:2747 → 2787
      EGF; Epidermal growth factor-like domain
      cd00054
      Location:2788 → 2826
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:2306 → 2491
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:2271 → 2301
      EGF; EGF-like domain
      pfam01049
      Location:2872 → 3003
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:2510 → 2552
      DUF3844; Domain of unknown function (DUF3844)
      cl09101
      Location:395 → 465
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    9. XM_064356931.1 → XP_064213001.1  neural-cadherin isoform X11

      UniProtKB/TrEMBL
      A0A139WH45

    10. XM_064356930.1 → XP_064213000.1  neural-cadherin isoform X10

      UniProtKB/TrEMBL
      A0A139WH45

    11. XM_064356929.1 → XP_064212999.1  neural-cadherin isoform X9

      UniProtKB/TrEMBL
      A0A139WH45

    12. XM_015980206.2 → XP_015835692.1  neural-cadherin isoform X12

      Conserved Domains (6) summary
      cd11304
      Location:488 → 584
      Cadherin_repeat; Cadherin tandem repeat domain
      cd00054
      Location:1487 → 1525
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00110
      Location:1003 → 1188
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:968 → 998
      EGF; EGF-like domain
      pfam01049
      Location:1570 → 1701
      Cadherin_C; Cadherin cytoplasmic region
      pfam12955
      Location:1207 → 1249
      DUF3844; Domain of unknown function (DUF3844)
    Nucleotide Protein Strain
    Heading Accession and Version

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