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    ccdc80l1 coiled-coil domain containing 80 like 1 [ Danio rerio (zebrafish) ]

    Gene ID: 569128, updated on 25-Apr-2024

    Summary

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    Official Symbol
    ccdc80l1provided by ZNC
    Official Full Name
    coiled-coil domain containing 80 like 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120328-4
    See related
    Ensembl:ENSDARG00000030975 AllianceGenome:ZFIN:ZDB-GENE-120328-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Acts upstream of or within axon guidance. Is expressed in several structures, including adaxial cell; caudal vein plexus; muscle; ovary; and somite. Orthologous to human CCDC80 (coiled-coil domain containing 80). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See ccdc80l1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (16406605..16422543)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (16279763..16295605)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 Neighboring gene Fas apoptotic inhibitory molecule b Neighboring gene solute carrier family 19 member 2 Neighboring gene zgc:161969

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Ccdc80-l1 Is involved in axon pathfinding of zebrafish motoneurons. Brusegan C, et al. PLoS One, 2012. PMID 22384085, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of cell-substrate adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in basement membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 80
    Names
    coiled-coil domain-containing protein 80-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      16406605..16422543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_692493.7 → XP_697585.4  coiled-coil domain-containing protein 80

      UniProtKB/TrEMBL
      A0A8N7TBQ4, E7FD69
      Related
      ENSDARP00000040034.6, ENSDART00000040035.8
      Conserved Domains (1) summary
      pfam13778
      Location:531 → 663
      DUF4174; Domain of unknown function (DUF4174)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials