cd81b CD81 molecule b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cd81bprovided by ZNC
Official Full Name: CD81 molecule bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040808-52
See related: Ensembl:ENSDARG00000022437 AllianceGenome:ZFIN:ZDB-GENE-040808-52
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92411
Summary: Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in cerebellum; cleithrum; floor plate; and hindbrain. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD81 (CD81 molecule). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (27318641..27336155)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (27336263..27353777)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: CD81 molecule b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003735.1 → NP_001003735.1 CD81 molecule b

See identical proteins and their annotated locations for NP_001003735.1

Status: PROVISIONAL

Source sequence(s)

BC078389

UniProtKB/TrEMBL

B2GRC9, F6NIK7, Q6AZB9

Related

ENSDARP00000036831.5, ENSDART00000037813.6

Conserved Domains (2) summary

cd03151
Location:113 → 204

CD81_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD81_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

pfam00335
Location:9 → 232

Tetraspannin; Tetraspanin family