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    PAK6 p21 (RAC1) activated kinase 6 [ Gallus gallus (chicken) ]

    Gene ID: 428837, updated on 3-Apr-2024

    Summary

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    Symbol
    PAK6provided by CGNC
    Full Name
    p21 (RAC1) activated kinase 6provided by CGNC
    Primary source
    CGNC:3583
    See related
    Ensembl:ENSGALG00010023257
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See PAK6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (814999..841925)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (809613..836538)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene cadherin related family member 5 Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene phospholipase C beta 2 Neighboring gene InaF motif containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase PAK 6
    Names
    p21 protein (Cdc42/Rac)-activated kinase 6
    p21(CDKN1A)-activated kinase 6
    XP_004941346.1
    XP_004941348.1
    XP_015141765.1
    XP_040528533.1
    XP_040528534.1
    XP_040528539.1
    XP_040528541.1
    XP_040557443.1
    XP_046775036.1
    XP_046798142.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      814999..841925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046942186.1 → XP_046798142.1  serine/threonine-protein kinase PAK 6 isoform X2

    2. XM_004941289.4 → XP_004941346.1  serine/threonine-protein kinase PAK 6 isoform X1

      See identical proteins and their annotated locations for XP_004941346.1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    3. XM_040701509.2 → XP_040557443.1  serine/threonine-protein kinase PAK 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Related
      ENSGALP00010034453.1, ENSGALT00010056711.1
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    4. XM_015286279.3 → XP_015141765.1  serine/threonine-protein kinase PAK 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    5. XM_004941291.5 → XP_004941348.1  serine/threonine-protein kinase PAK 6 isoform X2

      See identical proteins and their annotated locations for XP_004941348.1

      UniProtKB/TrEMBL
      A0A8V0ZM37
      Related
      ENSGALP00010034445.1, ENSGALT00010056703.1
      Conserved Domains (2) summary
      cd01093
      Location:10 → 55
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:371 → 667
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      809613..836538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046919080.1 → XP_046775036.1  serine/threonine-protein kinase PAK 6 isoform X2

    2. XM_040672599.2 → XP_040528533.1  serine/threonine-protein kinase PAK 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    3. XM_040672605.2 → XP_040528539.1  serine/threonine-protein kinase PAK 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    4. XM_040672600.2 → XP_040528534.1  serine/threonine-protein kinase PAK 6 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZM37, A0A8V0ZSD2
      Conserved Domains (2) summary
      cd01093
      Location:14 → 59
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:375 → 671
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

    5. XM_040672607.2 → XP_040528541.1  serine/threonine-protein kinase PAK 6 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZM37
      Conserved Domains (2) summary
      cd01093
      Location:10 → 55
      CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
      cd06659
      Location:371 → 667
      STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    Nucleotide Protein Strain
    Heading Accession and Version

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