DPH6 diphthamine biosynthesis 6 [Gallus gallus (chicken)] - Gene

Summary

Symbol: DPH6provided by CGNC
Full Name: diphthamine biosynthesis 6provided by CGNC
Primary source: CGNC:14194
See related: Ensembl:ENSGALG00010005407
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: ATPBD4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (31364214..31657896)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (31327242..31639314)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables diphthine-ammonia ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein histidyl modification to diphthamide	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: diphthine--ammonia ligase

Names: ATP binding domain 4; ATP-binding domain-containing protein 4

NP_001186639.1

EC 6.3.1.14

NP_001385331.1

EC 6.3.1.14

NP_001385332.1

EC 6.3.1.14

NP_001385333.1

EC 6.3.1.14

XP_015142835.4

EC 6.3.1.14

XP_015142837.4

EC 6.3.1.14

XP_040556909.1

EC 6.3.1.14

XP_046774455.1

EC 6.3.1.14

XP_046774456.1

EC 6.3.1.14

XP_046774457.1

EC 6.3.1.14

XP_046774458.1

EC 6.3.1.14

XP_046774459.1

EC 6.3.1.14

XP_046774460.1

EC 6.3.1.14

XP_046774461.1

EC 6.3.1.14

XP_046774462.1

EC 6.3.1.14

XP_046774463.1

EC 6.3.1.14

XP_046774464.1

EC 6.3.1.14

XP_046774465.1

EC 6.3.1.14

XP_046774466.1

EC 6.3.1.14

XP_046774467.1

EC 6.3.1.14

XP_046774468.1

EC 6.3.1.14

XP_046774469.1

EC 6.3.1.14

XP_046774470.1

EC 6.3.1.14

XP_046774471.1

EC 6.3.1.14

XP_046774472.1

EC 6.3.1.14

XP_046774473.1

EC 6.3.1.14

XP_046774474.1

EC 6.3.1.14

XP_046797698.1

EC 6.3.1.14

XP_046797699.1

EC 6.3.1.14

XP_046797700.1

EC 6.3.1.14

XP_046797701.1

EC 6.3.1.14

XP_046797702.1

EC 6.3.1.14

XP_046797703.1

EC 6.3.1.14

XP_046797704.1

EC 6.3.1.14

XP_046797705.1

EC 6.3.1.14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199710.3 → NP_001186639.1 diphthine--ammonia ligase isoform 3

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/TrEMBL

A0A8V0XL55

Conserved Domains (3) summary

cd06155
Location:258 → 360

eu_AANH_C_1; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the first of these ...

cd06156
Location:393 → 516

eu_AANH_C_2; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the second of these ...

cd01994
Location:1 → 167

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
NM_001398402.1 → NP_001385331.1 diphthine--ammonia ligase isoform 1

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/TrEMBL

A0A8V0XL55

Related

ENSGALP00010007438.1, ENSGALT00010012876.1
NM_001398403.1 → NP_001385332.1 diphthine--ammonia ligase isoform 2

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/TrEMBL

A0A8V0XL55

Conserved Domains (3) summary

cd06155
Location:290 → 392

eu_AANH_C_1; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the first of these ...

cd06156
Location:425 → 548

eu_AANH_C_2; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the second of these ...

cd01994
Location:1 → 199

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
NM_001398404.1 → NP_001385333.1 diphthine--ammonia ligase isoform 4

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/TrEMBL

A0A8V0XL55

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

31364214..31657896

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046941744.1 → XP_046797700.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046941743.1 → XP_046797699.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046941742.1 → XP_046797698.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_040700975.2 → XP_040556909.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8V0XL55

Conserved Domains (3) summary

cd06155
Location:258 → 360

eu_AANH_C_1; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the first of these ...

cd06156
Location:393 → 516

eu_AANH_C_2; A group of hypothetical eukaryotic proteins, characterized by the presence of an adenine nucleotide alpha hydrolase (AANH)-like domain located N-terminal to two distinctly different YjgF-YER057c-UK114-like domains. This CD contains the second of these ...

cd01994
Location:1 → 167

Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...
XM_046941745.1 → XP_046797701.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046941746.1 → XP_046797702.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046941747.1 → XP_046797703.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046941748.1 → XP_046797704.1 diphthine--ammonia ligase isoform X2

UniProtKB/TrEMBL

A0A8V0XL55
XM_015287349.4 → XP_015142835.4 diphthine--ammonia ligase isoform X5

UniProtKB/TrEMBL

A0A8V0XL50, A0A8V0XL55

Related

ENSGALP00010007426.1, ENSGALT00010012864.1
XM_015287351.4 → XP_015142837.4 diphthine--ammonia ligase isoform X6
XM_046941749.1 → XP_046797705.1 diphthine--ammonia ligase isoform X4

UniProtKB/TrEMBL

A0A8V0XL55

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

31327242..31639314

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046918501.1 → XP_046774457.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918507.1 → XP_046774463.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918499.1 → XP_046774455.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918503.1 → XP_046774459.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918500.1 → XP_046774456.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918509.1 → XP_046774465.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918505.1 → XP_046774461.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918502.1 → XP_046774458.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918515.1 → XP_046774471.1 diphthine--ammonia ligase isoform X9

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918516.1 → XP_046774472.1 diphthine--ammonia ligase isoform X3

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918504.1 → XP_046774460.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918506.1 → XP_046774462.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918508.1 → XP_046774464.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918512.1 → XP_046774468.1 diphthine--ammonia ligase isoform X7

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918510.1 → XP_046774466.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918511.1 → XP_046774467.1 diphthine--ammonia ligase isoform X1

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918513.1 → XP_046774469.1 diphthine--ammonia ligase isoform X2

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918514.1 → XP_046774470.1 diphthine--ammonia ligase isoform X8

UniProtKB/TrEMBL

A0A8V0XL55
XM_046918518.1 → XP_046774474.1 diphthine--ammonia ligase isoform X10
XM_046918517.1 → XP_046774473.1 diphthine--ammonia ligase isoform X4

UniProtKB/TrEMBL

A0A8V0XL55