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    RUNX1 runt-related transcription factor 1 [ Gallus gallus (chicken) ]

    Gene ID: 396152, updated on 6-Jun-2024

    Summary

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    Official Symbol
    RUNX1provided by CGNC
    Official Full Name
    runt-related transcription factor 1provided by CGNC
    Primary source
    CGNC:49673
    See related
    Ensembl:ENSGALG00010012917
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See RUNX1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (106105351..106258778, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (106194444..106348068, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene chloride intracellular channel 6 Neighboring gene uncharacterized LOC121109467 Neighboring gene uncharacterized LOC101748524 Neighboring gene uncharacterized LOC121109468 Neighboring gene uncharacterized LOC121109469

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of runtB is modulated during chondrocyte differentiation. Castagnola P, et al. Exp Cell Res, 1996 Mar 15. PMID 8601397

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hemopoiesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    runt-related transcription factor 1
    Names
    ch-runtB2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396968.1 → NP_001383897.1  runt-related transcription factor 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000020
      UniProtKB/TrEMBL
      A0A3Q2TTQ9, A0A8V0YGK4
      Related
      ENSGALP00010018026.1, ENSGALT00010031015.1
      Conserved Domains (2) summary
      pfam00853
      Location:67 → 193
      Runt; Runt domain
      pfam08504
      Location:380 → 472
      RunxI; Runx inhibition domain

    2. NM_205227.2 → NP_990558.1  runt-related transcription factor 1 isoform 2

      See identical proteins and their annotated locations for NP_990558.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000020
      UniProtKB/TrEMBL
      A0A8V0YGK4, F6RII4, Q90813
      Related
      ENSGALP00010018021.1, ENSGALT00010031008.1
      Conserved Domains (2) summary
      pfam00853
      Location:67 → 193
      Runt; Runt domain
      pfam08504
      Location:316 → 408
      RunxI; Runx inhibition domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      106105351..106258778 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015299305.4 → XP_015154791.1  runt-related transcription factor 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YGK4, F6RII4, Q90813
      Conserved Domains (2) summary
      pfam00853
      Location:67 → 193
      Runt; Runt domain
      pfam08504
      Location:316 → 408
      RunxI; Runx inhibition domain

    2. XM_025146751.3 → XP_025002519.1  runt-related transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YGK4
      Conserved Domains (2) summary
      pfam00853
      Location:67 → 193
      Runt; Runt domain
      pfam08504
      Location:386 → 478
      RunxI; Runx inhibition domain

    3. XM_025146753.3 → XP_025002521.1  runt-related transcription factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YGK4, A0A8V0YPE4
      Related
      ENSGALP00010018018.1, ENSGALT00010031002.1
      Conserved Domains (2) summary
      pfam00853
      Location:54 → 180
      Runt; Runt domain
      pfam08504
      Location:373 → 465
      RunxI; Runx inhibition domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      106194444..106348068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046906807.1 → XP_046762763.1  runt-related transcription factor 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YGK4, F6RII4, Q90813

    2. XM_046906805.1 → XP_046762761.1  runt-related transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YGK4

    3. XM_046906806.1 → XP_046762762.1  runt-related transcription factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YGK4, A0A8V0YPE4
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials