mid1ip1l MID1 interacting protein 1, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mid1ip1lprovided by ZNC
Official Full Name: MID1 interacting protein 1, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1697
See related: Ensembl:ENSDARG00000018145 AllianceGenome:ZFIN:ZDB-GENE-030131-1697
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: aur; g12l; fb78b10; mid1ip1; sb:cb505; zgc:55658; zgc:55736; wu:fb78b10; wu:fj81h03; zgc:112497
Summary: Acts upstream of or within regulation of cytoskeleton organization and regulation of ribonucleoprotein complex localization. Predicted to be located in cytoplasm; microtubule; and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including blastomere; hindbrain neural plate; nervous system; polster; and yolk syncytial layer. Orthologous to several human genes including H2AC11 (H2A clustered histone 11); H2AC21 (H2A clustered histone 21); and H2AC6 (H2A clustered histone 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 14

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (41466369..41468993, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (41099115..41101739, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

in embryos mutant for the cytoskeletal regulator mid1ip1l, germ plasm ribonucleoparticles fail to become recruited to the furrow, accumulating instead at the periphery of the blastodisc.
Title: Modulation of F-actin dynamics by maternal Mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo.
This study finds that maternally provided aura (mid1ip1l) acts during the reorganization of the cytoskeleton at the egg-to-embryo transition and highlight the importance of cytoskeletal dynamics and membrane recycling during this developmental period.
Title: aura (mid1ip1l) regulates the cytoskeleton at the zebrafish egg-to-embryo transition.

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General gene information

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Markers

fe13a01.y1 (e-PCR)
- UniSTS:196129

fa11g01.r1 (e-PCR)
- UniSTS:189586

fb78b10.x1 (e-PCR)
- UniSTS:191409

fb78b10.x1 (e-PCR)
- UniSTS:191410

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of lipid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of ribonucleoprotein complex localization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mid1-interacting protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.