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    QCR10 ubiquinol--cytochrome-c reductase subunit 10 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856390, updated on 13-Apr-2024

    Summary

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    Gene symbol
    QCR10
    Gene description
    ubiquinol--cytochrome-c reductase subunit 10
    Primary source
    SGD:S000003529
    Locus tag
    YHR001W-A
    See related
    AllianceGenome:SGD:S000003529
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to ubiquinol-cytochrome-c reductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Part of mitochondrial respiratory chain complex III. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: VIII
    Exon count:
    2
    Sequence:
    Chromosome: VIII; NC_001140.6 (107826..108122)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L14B Neighboring gene oxysterol-binding protein related protein OSH7 Neighboring gene coenzyme A transporter Neighboring gene tRNA threonylcarbamoyladenosine dehydratase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The respiratory chain in yeast behaves as a single functional unit. Boumans H, et al. J Biol Chem, 1998 Feb 27. PMID 9478928
    2. Isolation and characterization of QCR10, the nuclear gene encoding the 8.5-kDa subunit 10 of the Saccharomyces cerevisiae cytochrome bc1 complex. Brandt U, et al. J Biol Chem, 1994 Apr 29. PMID 8175712
    3. Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane. Zara V, et al. FEBS J, 2009 Apr. PMID 19236481, Free PMC Article
    4. Whole-Genome Approach to Understanding the Mechanism of Action of a Histatin 5-Derived Peptide. Bullock CB, et al. Antimicrob Agents Chemother, 2020 Feb 21. PMID 31843998, Free PMC Article
    5. Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b. Zara V, et al. Eur J Biochem, 2004 Mar. PMID 15009199

    See all (64) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in aerobic respiration IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial respiratory chain complex III IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial respiratory chain complex III IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ubiquinol--cytochrome-c reductase subunit 10
    NP_011864.1
    • Subunit of the ubiqunol-cytochrome c oxidoreductase complex; this complex comprises part of the mitochondrial respiratory chain; members include Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      107826..108122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181426.1 → NP_011864.1  TPA: ubiquinol--cytochrome-c reductase subunit 10 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011864.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKR8, O13538, P37299, Q9T2W2
      UniProtKB/TrEMBL
      A6ZSQ3, B3LSB9, C8ZA67, G2WF67, N1P352
      Conserved Domains (1) summary
      pfam09796
      Location:15 → 76
      QCR10; Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    6HU9_J.1
    6HU9_U.1
    6T0B_J.1
    6T0B_U.1
    6T15_J.1
    6T15_U.1
    P37299.2

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