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    RRT8 Rrt8p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854109, updated on 27-Jan-2024

    Summary

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    Gene symbol
    RRT8
    Gene description
    Rrt8p
    Primary source
    SGD:S000005408
    Locus tag
    YOL048C
    See related
    AllianceGenome:SGD:S000005408
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore wall assembly. Located in ascospore wall and prospore membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XV
    Exon count:
    2
    Sequence:
    Chromosome: XV; NC_001147.6 (240204..241310, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Gal11p Neighboring gene glutathione synthase Neighboring gene Lds2p Neighboring gene serine/threonine protein kinase PSK2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Conserved Machinery Underlies the Synthesis of a Chitosan Layer in the Candida Chlamydospore Cell Wall. Bemena LD, et al. mSphere, 2021 Apr 28. PMID 33910989, Free PMC Article
    2. In vitro reconstitution of the yeast spore wall dityrosine layer discloses the mechanism of its assembly. Bemena LD, et al. J Biol Chem, 2017 Sep 22. PMID 28794156, Free PMC Article
    3. Lipid droplet proteins, Lds1p, Lds2p, and Rrt8p, are implicated in membrane protein transport associated with ergosterol. Ueno K, et al. Biochem Biophys Res Commun, 2016 Jul 8. PMID 27216456
    4. Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae. Hontz RD, et al. Genetics, 2009 May. PMID 19270272, Free PMC Article
    5. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Lin CP, et al. PLoS Genet, 2013. PMID 23966878, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ascospore wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ascospore wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lipid droplet HDA PubMed 
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in prospore membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spore wall IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rrt8p
    NP_014594.2
    • Protein involved in spore wall assembly; shares similarity with Lds1p and Lds2p and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      240204..241310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183302.1 → NP_014594.2  TPA: Rrt8p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014594.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W219, Q08219, Q870H5
      UniProtKB/TrEMBL
      B3LJ11, N1NWQ8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08219.2

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