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    MASTL microtubule associated serine/threonine kinase like [ Bos taurus (cattle) ]

    Gene ID: 540206, updated on 5-Mar-2024

    Summary

    Official Symbol
    MASTLprovided by VGNC
    Official Full Name
    microtubule associated serine/threonine kinase likeprovided by VGNC
    Primary source
    VGNC:VGNC:31260
    See related
    BGD:BT24071; Ensembl:ENSBTAG00000017271
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GW; GWL; MAST-L
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (17749343..17773664)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346881 Neighboring gene YME1 like 1 ATPase Neighboring gene cytosolic iron-sulfur assembly component 2A-like Neighboring gene chromobox protein homolog 3-like Neighboring gene acyl-CoA binding domain containing 5 Neighboring gene abl interactor 1 Neighboring gene decaprenyl diphosphate synthase subunit 1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein kinase greatwall
    Names
    microtubule-associated serine/threonine-protein kinase-like
    NP_001107237.1
    XP_005214293.1
    XP_024856540.1
    XP_024856541.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113765.1NP_001107237.1  serine/threonine-protein kinase greatwall

      See identical proteins and their annotated locations for NP_001107237.1

      Status: INFERRED

      Source sequence(s)
      NKLS02000013
      UniProtKB/Swiss-Prot
      E1BFR5
      UniProtKB/TrEMBL
      G5E5K2
      Related
      ENSBTAP00000082836.1, ENSBTAT00000088336.1
      Conserved Domains (3) summary
      smart00220
      Location:35198
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05610
      Location:30223
      STKc_MASTL; Catalytic domain of the Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase (also called greatwall kinase)
      cl21453
      Location:680871
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17749343..17773664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005214236.5XP_005214293.1  serine/threonine-protein kinase greatwall isoform X1

      UniProtKB/Swiss-Prot
      E1BFR5
      Related
      ENSBTAP00000022950.6, ENSBTAT00000022950.7
      Conserved Domains (3) summary
      smart00220
      Location:35198
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05610
      Location:30223
      STKc_MASTL; Catalytic domain of the Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase (also called greatwall kinase)
      cl21453
      Location:680872
      PKc_like; Protein Kinases, catalytic domain
    2. XM_025000772.2XP_024856540.1  serine/threonine-protein kinase greatwall isoform X2

      UniProtKB/Swiss-Prot
      E1BFR5
      Related
      ENSBTAP00000083557.1, ENSBTAT00000129759.1
      Conserved Domains (2) summary
      cd05610
      Location:30223
      STKc_MASTL; Catalytic domain of the Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase (also called greatwall kinase)
      cl21453
      Location:680834
      PKc_like; Protein Kinases, catalytic domain
    3. XM_025000773.2XP_024856541.1  serine/threonine-protein kinase greatwall isoform X3

      UniProtKB/Swiss-Prot
      E1BFR5
      Conserved Domains (2) summary
      cd05610
      Location:30223
      STKc_MASTL; Catalytic domain of the Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase (also called greatwall kinase)
      cl21453
      Location:680833
      PKc_like; Protein Kinases, catalytic domain