U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SCARB2 scavenger receptor class B member 2 [ Sus scrofa (pig) ]

    Gene ID: 414407, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SCARB2provided by VGNC
    Official Full Name
    scavenger receptor class B member 2provided by VGNC
    Primary source
    VGNC:VGNC:92614
    See related
    Ensembl:ENSSSCG00000008980
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in ovary (RPKM 98.9), lung (RPKM 68.5) and 8 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 8
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 8 NC_010450.4 (71838395..71910461, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 8 NC_010450.3 (76034114..76105880, complement)

    Chromosome 8 - NC_010450.4Genomic Context describing neighboring genes Neighboring gene ADP-ribosyltransferase 3 (inactive) Neighboring gene C-X-C motif chemokine ligand 11 Neighboring gene nucleoporin 54 Neighboring gene family with sequence similarity 47 member E Neighboring gene starch binding domain 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Assignment of the scavenger receptor class B, member 2 gene (SCARB2) to porcine chromosome 8q11-->q12 by somatic cell and radiation hybrid panel mapping. Kim JW, et al. Cytogenet Genome Res, 2006. PMID 16484799
    2. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
    3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Gene mapped to chromosome 8 in swine
      Title: Assignment of the scavenger receptor class B, member 2 gene (SCARB2) to porcine chromosome 8q11-->q12 by somatic cell and radiation hybrid panel mapping.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein targeting to lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in receptor-mediated endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of glucosylceramidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    lysosome membrane protein 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001244155.1 → NP_001231084.1  lysosome membrane protein 2 precursor

      Status: VALIDATED

      Source sequence(s)
      FP016186
      UniProtKB/TrEMBL
      A0A4X1SYC5, A0A8D0NS64, A0A8D1FY78, A0A8D1UJE7, F1RYT3
      Related
      ENSSSCP00000065874.2, ENSSSCT00000068222.2
      Conserved Domains (1) summary
      pfam01130
      Location:28 → 455
      CD36; CD36 family

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010450.4 Reference Sscrofa11.1 Primary Assembly

      Range
      71838395..71910461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005666776.2 → XP_005666833.1  lysosome membrane protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A480ITG5, A0A5G2QMJ7, A0A8D1FUA6
      Conserved Domains (1) summary
      pfam01130
      Location:28 → 455
      CD36; CD36 family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Miscellaneous