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    H2BC20P H2B clustered histone 20, pseudogene [ Homo sapiens (human) ]

    Gene ID: 337873, updated on 10-Oct-2023

    Summary

    Official Symbol
    H2BC20Pprovided by HGNC
    Official Full Name
    H2B clustered histone 20, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:20516
    See related
    Ensembl:ENSG00000261716 AllianceGenome:HGNC:20516
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LETN; H2B/t; HIST2H2BC; HIST2H2BD
    Summary
    Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is found in a histone cluster on chromosome 1. [provided by RefSeq, Oct 2015]
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    Genomic context

    Location:
    1q21.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (149850192..149850773, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (148974332..148974913, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (149821759..149822340, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H2A clustered histone 18 Neighboring gene H2B clustered histone 19, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:149816892-149817655 Neighboring gene H4 clustered histone 15 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:149822691-149823368 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:149824048-149824725 Neighboring gene H2A clustered histone 19 Neighboring gene H3 clustered histone 15

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Other Names

    • histone 2, H2bc
    • histone H2B/s
    • histone cluster 2 H2B family member c (pseudogene)
    • histone cluster 2, H2bc (pseudogene)
    • lncRNA essential for tumor cell proliferation via NPM1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036461.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AL591493
      Related
      ENST00000498492.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      149850192..149850773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      148974332..148974913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)