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    NRAP nebulin related anchoring protein [ Bos taurus (cattle) ]

    Gene ID: 532640, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NRAPprovided by VGNC
    Official Full Name
    nebulin related anchoring proteinprovided by VGNC
    Primary source
    VGNC:VGNC:32251
    See related
    BGD:BT24988; Ensembl:ENSBTAG00000019327
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NRAP in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (34061553..34136928, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene vesicle transport through interaction with t-SNAREs 1A Neighboring gene transcription factor 7 like 2 Neighboring gene hyaluronan binding protein 2 Neighboring gene caspase 7 Neighboring gene pleckstrin homology domain containing S1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Demographic History, Adaptation, and NRAP Convergent Evolution at Amino Acid Residue 100 in the World Northernmost Cattle from Siberia. Buggiotti L, et al. Mol Biol Evol, 2021 Jul 29. PMID 33784744, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Demographic History, Adaptation, and NRAP Convergent Evolution at Amino Acid Residue 100 in the World Northernmost Cattle from Siberia.
      Title: Demographic History, Adaptation, and NRAP Convergent Evolution at Amino Acid Residue 100 in the World Northernmost Cattle from Siberia.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC155323

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cardiac muscle thin filament assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nebulin-related-anchoring protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098072.1 → NP_001091541.1  nebulin-related-anchoring protein

      See identical proteins and their annotated locations for NP_001091541.1

      Status: PROVISIONAL

      Source sequence(s)
      BC140607
      UniProtKB/TrEMBL
      A5D7L9, F1MMX2
      Related
      ENSBTAP00000064771.2, ENSBTAT00000084925.2
      Conserved Domains (3) summary
      smart00227
      Location:727 → 757
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:316 → 342
      Nebulin; Nebulin repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34061553..34136928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024985667.2 → XP_024841435.1  nebulin-related-anchoring protein isoform X6

      UniProtKB/TrEMBL
      F1MMX2
      Related
      ENSBTAP00000070016.2, ENSBTAT00000080413.2
      Conserved Domains (3) summary
      smart00227
      Location:692 → 722
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat

    2. XM_005225747.4 → XP_005225804.2  nebulin-related-anchoring protein isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LNP2, F1MMX2
      Related
      ENSBTAP00000025740.7, ENSBTAT00000025740.7
      Conserved Domains (3) summary
      smart00227
      Location:692 → 722
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat

    3. XM_024985666.2 → XP_024841434.1  nebulin-related-anchoring protein isoform X5

      UniProtKB/TrEMBL
      A0A3Q1M815, F1MMX2
      Conserved Domains (3) summary
      smart00227
      Location:727 → 757
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat

    4. XM_005225746.4 → XP_005225803.2  nebulin-related-anchoring protein isoform X2

      UniProtKB/TrEMBL
      F1MMX2
      Related
      ENSBTAP00000061644.2, ENSBTAT00000073580.2
      Conserved Domains (3) summary
      smart00227
      Location:693 → 723
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat

    5. XM_010820038.4 → XP_010818340.2  nebulin-related-anchoring protein isoform X3

      UniProtKB/TrEMBL
      F1MMX2
      Conserved Domains (3) summary
      smart00227
      Location:728 → 758
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat

    6. XM_005225745.4 → XP_005225802.2  nebulin-related-anchoring protein isoform X1

      UniProtKB/TrEMBL
      F1MMX2
      Conserved Domains (3) summary
      smart00227
      Location:728 → 758
      NEBU; The Nebulin repeat is present also in Las1
      cd09446
      Location:6 → 58
      LIM_N_RAP; The LIM domain of N-RAP
      pfam00880
      Location:209 → 234
      Nebulin; Nebulin repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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