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    UBR4 ubiquitin protein ligase E3 component n-recognin 4 [ Bos taurus (cattle) ]

    Gene ID: 514561, updated on 6-Jun-2024

    Summary

    Official Symbol
    UBR4provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 4provided by VGNC
    Primary source
    VGNC:VGNC:36618
    See related
    BGD:BT14728; Ensembl:ENSBTAG00000015240
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See UBR4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    108
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (133452107..133589504)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA70 Neighboring gene MRT4 homolog, ribosome maturation factor Neighboring gene ER membrane protein complex subunit 1 Neighboring gene small nucleolar RNA U3 Neighboring gene U1 spliceosomal RNA

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase UBR4
    NP_001192721.1
    XP_024857115.1
    XP_059749304.1
    XP_059749308.1
    XP_059749311.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205792.1NP_001192721.1  E3 ubiquitin-protein ligase UBR4

      See identical proteins and their annotated locations for NP_001192721.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A0AAA9TU63
      Related
      ENSBTAP00000101912.1, ENSBTAT00000133057.1
      Conserved Domains (3) summary
      smart00396
      Location:16591726
      ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
      pfam12773
      Location:36583702
      DZR; Double zinc ribbon
      pfam13764
      Location:43655161
      E3_UbLigase_R4; E3 ubiquitin-protein ligase UBR4

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      133452107..133589504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059893321.1XP_059749304.1  E3 ubiquitin-protein ligase UBR4 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TU63
    2. XM_059893328.1XP_059749311.1  E3 ubiquitin-protein ligase UBR4 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TKM9
    3. XM_059893325.1XP_059749308.1  E3 ubiquitin-protein ligase UBR4 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TU63
    4. XM_025001347.2XP_024857115.1  E3 ubiquitin-protein ligase UBR4 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TU63, E1BHT5
      Related
      ENSBTAP00000020277.7, ENSBTAT00000020277.7
      Conserved Domains (3) summary
      smart00396
      Location:16591726
      ZnF_UBR1; Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway
      pfam12773
      Location:36863730
      DZR; Double zinc ribbon
      pfam13764
      Location:43935189
      E3_UbLigase_R4; E3 ubiquitin-protein ligase UBR4