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    L3MBTL2 L3MBTL histone methyl-lysine binding protein 2 [ Bos taurus (cattle) ]

    Gene ID: 513297, updated on 6-Jun-2024

    Summary

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    Official Symbol
    L3MBTL2provided by VGNC
    Official Full Name
    L3MBTL histone methyl-lysine binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:30763
    See related
    BGD:BT18629; Ensembl:ENSBTAG00000030222
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See L3MBTL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (112362253..112383952)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-1281 Neighboring gene E1A binding protein p300 Neighboring gene uncharacterized LOC112446777 Neighboring gene microRNA mir-2441 Neighboring gene chondroadherin like Neighboring gene Ran GTPase activating protein 1 Neighboring gene zinc finger CCCH-type containing 7B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139186

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal(3)malignant brain tumor-like protein 2
    Names
    L3MBTL2, polycomb repressive complex 1 subunit
    l(3)mbt-like 2 protein
    l(3)mbt-like protein 2
    lethal(3)malignant brain tumor-like 2 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075610.1 → NP_001069078.1  lethal(3)malignant brain tumor-like protein 2

      See identical proteins and their annotated locations for NP_001069078.1

      Status: PROVISIONAL

      Source sequence(s)
      BC116013
      UniProtKB/Swiss-Prot
      Q0V8P8, Q1JQD9
      UniProtKB/TrEMBL
      A0A3Q1MDJ1
      Related
      ENSBTAP00000037474.5, ENSBTAT00000037648.5
      Conserved Domains (2) summary
      smart00561
      Location:512 → 605
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam02820
      Location:434 → 501
      MBT; mbt repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      112362253..112383952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886330.1 → XP_059742313.1  lethal(3)malignant brain tumor-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MDJ1

    2. XM_059886328.1 → XP_059742311.1  lethal(3)malignant brain tumor-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MDJ1, A0A3Q1MS74
      Related
      ENSBTAP00000072805.2, ENSBTAT00000085264.2

    3. XM_059886329.1 → XP_059742312.1  lethal(3)malignant brain tumor-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MDJ1

    4. XM_005207391.5 → XP_005207448.1  lethal(3)malignant brain tumor-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MDJ1
      Conserved Domains (2) summary
      smart00561
      Location:512 → 605
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam02820
      Location:434 → 501
      MBT; mbt repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1JQD9.1 GenPept UniProtKB/Swiss-Prot:Q1JQD9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials