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Figure 1. Generic structure of ACV ProTides. From: A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
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Figure 3. ACV ProTides suppress HIV-1 replication in human cervicovaginal tissues and in HSV-2-coinfected tonsillar tissues. From: A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
Figure 2. ACV ProTides inhibit HIV-1 replication in human lymphoid tissues. From: A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
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