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Figure 1

Figure 1. From: Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study.

Metabolism of homocysteine and the remethylationto methionine by the alternative folate and betaine pathways. THF: tetrahydrofolate; MTHFR: methylentetrahydrofolate reductase; BHMT: betaine-homocysteine methyltransferase; MTR: methionine synthase reductase. Note: in boxes – choline, betaine, folate and methionine concentrations in plasma

Aurelian Bidulescu, et al. BMC Cardiovasc Disord. 2007;7:20-20.

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