(
a) The curves were produced by moving a 5 cm spherical balloon towards each sensor at a constant rate, starting at a distance of 8 cm and moving closer until the balloon and sensor were touching (0 cm). Maximum sensor range was defined as a 10% change in
resistance from baseline (
=0), which was determined to be the chance in signal necessary to overcome noise (SNR = 10). At the point where the signal is 10% of the maximum generated signal, we draw a vertical line and call it the distance threshold (the point at which we have overcome noise, as defined by the SNR, and we can be confident we are detecting changes in signal). The distance threshold is 4.97 cm for the large
coil (blue, 3.99 cm for the medium
coil (red), and 2.29 cm for the small
coil (yellow). As expected, maximum sensor range varied directly as a function of
coil size, with the largest
coil having the largest range and the smallest
coil having the smallest range. While the medium
coil rises much faster than the large
coil, the 10% threshold is lower, as expected, than the large
coil. Using these ranges, we can predict lesion depth based on the pattern of activated sensors. (
b) Tuning curves showing the change in
resistance as a function of volume in a solenoid
coil, demonstrating a volumetric dose–response relationship. These curves may be used to predict the volume of lesion.