α－丙烯基－二氯丙醇【有化】 - PMC

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Select item 107145041.

Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function

Jungnam Lee, Naweed Mohammad, Yuanqing Lu, Regina Oshins, Alek Aranyos, Mark Brantly

Respir Res. 2023; 24: 309. Published online 2023 Dec 11. doi: 10.1186/s12931-023-02605-0

PMCID:: PMC10714504

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Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

Nelson Ferreira, Hjalte Gram, Zachary A. Sorrentino, Emil Gregersen, Sissel Ida Schmidt, Lasse Reimer, Cristine Betzer, Clara Perez-Gozalbo, Marjo Beltoja, Madhu Nagaraj, Jie Wang, Jan S. Nowak, Mingdong Dong, Katarina Willén, Ersoy Cholak, Kaare Bjerregaard-Andersen, Nicolas Mendez, Prakruti Rabadia, Mohammad Shahnawaz, Claudio Soto, Daniel E. Otzen, Ümit Akbey, Morten Meyer, Benoit I. Giasson, Marina Romero-Ramos, Poul Henning Jensen

Acta Neuropathol. 2021; 142(1): 87–115. Published online 2021 May 12. doi: 10.1007/s00401-021-02316-0

PMCID:: PMC8217051

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Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation

Thomas J. Krzystek, Rupkatha Banerjee, Layne Thurston, JianQiao Huang, Kelsey Swinter, Saad Navid Rahman, Tomas L. Falzone, Shermali Gunawardena

Cell Death Dis. 2021 Sep; 12(9): 796. Published online 2021 Aug 17. doi: 10.1038/s41419-021-04046-3

PMCID:: PMC8371151

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Select item 98020614.

Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation

Lasse Reimer, Hjalte Gram, Nanna Møller Jensen, Cristine Betzer, Li Yang, Lorrain Jin, Min Shi, Driss Boudeffa, Giuliana Fusco, Alfonso De Simone, Deniz Kirik, Hilal A Lashuel, Jing Zhang, Poul Henning Jensen

PNAS Nexus. 2022 Nov; 1(5): pgac259. Published online 2022 Nov 16. doi: 10.1093/pnasnexus/pgac259

PMCID:: PMC9802061

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Challenges and recent advancements in the synthesis of α,α-disubstituted α-amino acids

Yu Zhang, Jaro Vanderghinste, Jinxin Wang, Shoubhik Das

Nat Commun. 2024; 15: 1474. Published online 2024 Feb 17. doi: 10.1038/s41467-024-45790-2

PMCID:: PMC10874380

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Monitoring alpha‐synuclein oligomerization and aggregation using bimolecular fluorescence complementation assays: What you see is not always what you get

Bryan Frey, Abdelrahman AlOkda, Matthew P. Jackson, Nathan Riguet, James A. Duce, Hilal A. Lashuel

J Neurochem. 2021 May; 157(4): 872–888. Published online 2020 Oct 27. doi: 10.1111/jnc.15147

PMCID:: PMC8246987

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The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons

Eric N. Anderson, Delnessaw Hirpa, Kan Hong Zheng, Rupkatha Banerjee, Shermali Gunawardena

Front Cell Neurosci. 2019; 13: 540. Published online 2020 Jan 10. doi: 10.3389/fncel.2019.00540

PMCID:: PMC6984405

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Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein

Shujing Zhang, Ruowei Zhu, Buyan Pan, Hong Xu, Modupe F. Olufemi, Ronald J. Gathagan, Yuanxi Li, Luyan Zhang, Jasmine Zhang, Wenxuan Xiang, Eliot Masahiro Kagan, Xingjun Cao, Chaoxing Yuan, Soo-Jung Kim, Christopher K. Williams, Shino Magaki, Harry V. Vinters, Hilal A. Lashuel, Benjamin A. Garcia, E. James Petersson, John Q. Trojanowski, Virginia M.-Y. Lee, Chao Peng

Nat Neurosci. Author manuscript; available in PMC 2023 Apr 14.

Published in final edited form as: Nat Neurosci. 2023 Feb; 26(2): 213–225. Published online 2023 Jan 23. doi: 10.1038/s41593-022-01239-7

Correction in:: Nat Neurosci. 2023 Oct 9

PMCID:: PMC10103650

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Alpha-Synuclein and Lipids: The Elephant in the Room?

Alessia Sarchione, Antoine Marchand, Jean-Marc Taymans, Marie-Christine Chartier-Harlin

Cells. 2021 Sep; 10(9): 2452. Published online 2021 Sep 17. doi: 10.3390/cells10092452

PMCID:: PMC8467310

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Pathogenesis of α-Synuclein in Parkinson’s Disease: From a Neuron-Glia Crosstalk Perspective

Shuanglong Yi, Linfang Wang, Honglei Wang, Margaret S. Ho, Shiping Zhang

Int J Mol Sci. 2022 Dec; 23(23): 14753. Published online 2022 Nov 25. doi: 10.3390/ijms232314753

PMCID:: PMC9739123

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α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes

Aysegul Dilsizoglu Senol, Maura Samarani, Sylvie Syan, Carlos M. Guardia, Takashi Nonaka, Nalan Liv, Patricia Latour-Lambert, Masato Hasegawa, Judith Klumperman, Juan S. Bonifacino, Chiara Zurzolo

PLoS Biol. 2021 Jul; 19(7): e3001287. Published online 2021 Jul 20. doi: 10.1371/journal.pbio.3001287

PMCID:: PMC8291706

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Architecture, Function, Regulation, and Evolution of α-Glucans Metabolic Enzymes in Prokaryotes

Javier O. Cifuente, Christophe Colleoni, Rainer Kalscheuer, Marcelo E. Guerin

Chem Rev. 2024 Apr 24; 124(8): 4863–4934. Published online 2024 Apr 12. doi: 10.1021/acs.chemrev.3c00811

PMCID:: PMC11046441

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Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers

Shenjie Wu, Nancy C Hernandez Villegas, Daniel W Sirkis, Iona Thomas-Wright, Richard Wade-Martins, Randy Schekman

eLife. 2023; 12: e85837. Published online 2023 Jan 10. doi: 10.7554/eLife.85837

PMCID:: PMC9876576

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α-Synuclein Pathology and Reduced Neurogenesis in the Olfactory System Affect Olfaction in a Mouse Model of Parkinson's Disease

Eduardo Martin-Lopez, D. J. Vidyadhara, Teresa Liberia, Sarah J. Meller, Leah E. Harmon, Ryan M. Hsu, Natalie Spence, Bowen Brennan, Kimberly Han, Betül Yücel, Sreeganga S. Chandra, Charles A. Greer

J Neurosci. 2023 Feb 8; 43(6): 1051–1071. doi: 10.1523/JNEUROSCI.1526-22.2022

PMCID:: PMC9908323

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“Janus-Faced” α-Synuclein: Role in Parkinson’s Disease

Bipul Ray, Arehally M. Mahalakshmi, Sunanda Tuladhar, Abid Bhat, Asha Srinivasan, Christophe Pellegrino, Anbarasu Kannan, Srinivasa Rao Bolla, Saravana Babu Chidambaram, Meena Kishore Sakharkar

Front Cell Dev Biol. 2021; 9: 673395. Published online 2021 May 28. doi: 10.3389/fcell.2021.673395

PMCID:: PMC8194081

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In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons

Maria Fouka, Panagiota Mavroeidi, Grigoria Tsaka, Maria Xilouri

Front Cell Dev Biol. 2020; 8: 559791. Published online 2020 Sep 4. doi: 10.3389/fcell.2020.559791

PMCID:: PMC7500083

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Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity

Larisa Ryskalin, Rosangela Ferese, Gabriele Morucci, Francesca Biagioni, Carla L. Busceti, Fabrizio Michetti, Paola Lenzi, Alessandro Frati, Francesco Fornai

Cancers (Basel) 2022 Mar; 14(6): 1382. Published online 2022 Mar 8. doi: 10.3390/cancers14061382

PMCID:: PMC8946689

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A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease

Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M. Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A. Fon, Armen Saghatelyan, Abid Oueslati

PLoS Biol. 2022 Mar; 20(3): e3001578. Published online 2022 Mar 9. doi: 10.1371/journal.pbio.3001578

PMCID:: PMC8936469

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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

Michael E. O’Brien, Grace Murray, Debananda Gogoi, Azeez Yusuf, Cormac McCarthy, Mark R. Wormald, Michelle Casey, Claudie Gabillard-Lefort, Noel G. McElvaney, Emer P. Reeves

Int J Mol Sci. 2022 Mar; 23(5): 2441. Published online 2022 Feb 23. doi: 10.3390/ijms23052441

PMCID:: PMC8910375

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Select item 889395720.

Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research

Weijin Liu, Qidi Zhang, Hao Xing, Ge Gao, Jia Liu, Yue Huang, Hui Yang

Front Neurol. 2022; 13: 821792. Published online 2022 Feb 17. doi: 10.3389/fneur.2022.821792

PMCID:: PMC8893957

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