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Select item 45541901.

Zodiac: A Comprehensive Depiction of Genetic Interactions in Cancer by Integrating TCGA Data

Yitan Zhu, Yanxun Xu, Donald L. Helseth, Jr, Kamalakar Gulukota, Shengjie Yang, Lorenzo L. Pesce, Riten Mitra, Peter Müller, Subhajit Sengupta, Wentian Guo, Jonathan C. Silverstein, Ian Foster, Nigel Parsad, Kevin P. White, Yuan Ji

J Natl Cancer Inst. 2015 Aug; 107(8): djv129. Published online 2015 May 8. doi: 10.1093/jnci/djv129

PMCID:: PMC4554190

Article PDF–12M

Select item 110158972.

Does Western or Chinese Zodiac Sign Predict COVID Infections and Death?

Amanda Frugoli, Sagar Parekh, Graal Diaz

Cureus. 2024 Mar; 16(3): e56165. Published online 2024 Mar 14. doi: 10.7759/cureus.56165

PMCID:: PMC11015897

Article PDF–479K

Select item 54829623.

Within-class differences in cancer risk for sulfonylurea treatments in patients with type 2 diabetes (ZODIAC-55) – a study protocol

Dennis Schrijnders, Geertruida H. de Bock, Sebastiaan T. Houweling, Kornelis J. J. van Hateren, Klaas H. Groenier, Jeffrey A. Johnson, Henk J. G. Bilo, Nanne Kleefstra, Gijs W. D. Landman

BMC Cancer. 2017; 17: 444. Published online 2017 Jun 23. doi: 10.1186/s12885-017-3433-z

PMCID:: PMC5482962

Article PDF–379K

Select item 57861414.

Association between body mass index and obesity-related cancer risk in men and women with type 2 diabetes in primary care in the Netherlands: a cohort study (ZODIAC-56)

Steven H Hendriks, Dennis Schrijnders, Kornelis JJ van Hateren, Klaas H Groenier, Sabine Siesling, Angela H E M Maas, Gijs W D Landman, Henk J G Bilo, N Kleefstra

BMJ Open. 2018; 8(1): e018859. Published online 2018 Jan 24. doi: 10.1136/bmjopen-2017-018859

PMCID:: PMC5786141

Article PDF–313K

Select item 43615495.

Comparison of Methods for Renal Risk Prediction in Patients with Type 2 Diabetes (ZODIAC-36)

Ineke J. Riphagen, Nanne Kleefstra, Iefke Drion, Alaa Alkhalaf, Merel van Diepen, Qi Cao, Klaas H. Groenier, Gijs W. D. Landman, Gerjan Navis, Henk J. G. Bilo, Stephan J. L. Bakker

PLoS One. 2015; 10(3): e0120477. Published online 2015 Mar 16. doi: 10.1371/journal.pone.0120477

PMCID:: PMC4361549

Article PDF–344K

Select item 103273956.

Both LDL and HDL particle concentrations associate positively with an increased risk of developing microvascular complications in patients with type 2 diabetes: lost protection by HDL (Zodiac-63)

Arno R. Bourgonje, Margery A. Connelly, Harry van Goor, Peter R. van Dijk, Robin P. F. Dullaart

Cardiovasc Diabetol. 2023; 22: 169. Published online 2023 Jul 6. doi: 10.1186/s12933-023-01909-1

PMCID:: PMC10327395

Article PDF–864K

Select item 57849057.

Sex differences in obesity related cancer incidence in relation to type 2 diabetes diagnosis (ZODIAC-49)

Dennis Schrijnders, Steven H. Hendriks, Nanne Kleefstra, Pauline A. J. Vissers, Jeffrey A. Johnson, Geertruida H. de Bock, Henk J. G. Bilo, Gijs W. D. Landman

PLoS One. 2018; 13(1): e0190870. Published online 2018 Jan 25. doi: 10.1371/journal.pone.0190870

PMCID:: PMC5784905

Article PDF–1.4M

Select item 34328498.

A prospective observational study of quality of diabetes care in a shared care setting: trends and age differences (ZODIAC-19)

Kornelis J J van Hateren, Iefke Drion, Nanne Kleefstra, Klaas H Groenier, Sebastiaan T Houweling, Klaas van der Meer, Henk J G Bilo

BMJ Open. 2012; 2(4): e001387. Published online 2012 Aug 29. doi: 10.1136/bmjopen-2012-001387

PMCID:: PMC3432849

Article PDF–264K

Select item 94965609.

The Paradoxical Role of Circulating Ketone Bodies in Glycemic Control of Individuals with Type 2 Diabetes: High Risk, High Reward?

Amarens van der Vaart, Martine G. E. Knol, Martin H. de Borst, Stephan J. L. Bakker, Margery A. Connelly, Erwin Garcia, Henk J. G. Bilo, Peter R. van Dijk, Robin P. F. Dullaart

Biomolecules. 2022 Sep; 12(9): 1318. Published online 2022 Sep 18. doi: 10.3390/biom12091318

PMCID:: PMC9496560

Article PDF–281K

Select item 512958510.

Addition of sulphonylurea to metformin does not relevantly change body weight: a prospective observational cohort study (ZODIAC‐39)

Dennis Schrijnders, Raiza Wever, Nanne Kleefstra, Sebastiaan T. Houweling, Kornelis J. J. van Hateren, Geertruida H. de Bock, Henk J. G. Bilo, Klaas H. Groenier, Gijs W. D. Landman

Diabetes Obes Metab. 2016 Oct; 18(10): 973–979. Published online 2016 Jul 13. doi: 10.1111/dom.12700

PMCID:: PMC5129585

Article PDF–143K

Select item 1060748411.

Plasma Citrate Levels Are Associated with an Increased Risk of Cardiovascular Mortality in Patients with Type 2 Diabetes (Zodiac-64)

Arno R. Bourgonje, Margery A. Connelly, Harry van Goor, Peter R. van Dijk, Robin P. F. Dullaart

J Clin Med. 2023 Oct; 12(20): 6670. Published online 2023 Oct 22. doi: 10.3390/jcm12206670

PMCID:: PMC10607484

Article PDF–622K

Select item 819737812.

Circulating Trimethylamine N-Oxide Is Associated with Increased Risk of Cardiovascular Mortality in Type-2 Diabetes: Results from a Dutch Diabetes Cohort (ZODIAC-59)

Jose L. Flores-Guerrero, Peter R. van Dijk, Margery A. Connelly, Erwin Garcia, Henk J. G. Bilo, Gerjan Navis, Stephan J. L. Bakker, Robin P. F. Dullaart

J Clin Med. 2021 Jun; 10(11): 2269. Published online 2021 May 24. doi: 10.3390/jcm10112269

PMCID:: PMC8197378

Article PDF–854K

Select item 440460313.

The relationship between N-terminal prosomatostatin, all-cause and cardiovascular mortality in patients with type 2 diabetes mellitus (ZODIAC-35)

Peter R van Dijk, Gijs WD Landman, Larissa van Essen, Joachim Struck, Klaas H Groenier, Henk JG Bilo, Stephan JL Bakker, Nanne Kleefstra

BMC Endocr Disord. 2015; 15: 19. Published online 2015 Apr 14. doi: 10.1186/s12902-015-0009-2

PMCID:: PMC4404603

Article PDF–556K

Select item 706419714.

Group meaningfulness and the causal direction of influence between the ingroup and the self or another individual: Evidence from the Induction-Deduction Paradigm

Mara Cadinu, Andrea Carnaghi, Francesca Guizzo

PLoS One. 2020; 15(3): e0229321. Published online 2020 Mar 10. doi: 10.1371/journal.pone.0229321

PMCID:: PMC7064197

Article PDF–780K

Select item 566523215.

Sex differences in survival of patients with type 2 diabetes in primary care (ZODIAC-50)

Steven H Hendriks, Kornelis J J van Hateren, Klaas H Groenier, Gijs W D Landman, Angela H E M Maas, Henk J G Bilo, Nanne Kleefstra

BMJ Open. 2017; 7(10): e015870. Published online 2017 Oct 25. doi: 10.1136/bmjopen-2017-015870

PMCID:: PMC5665232

Article PDF–496K

Select item 577426616.

Lifestyle and emotional well-being in men and women with type 2 diabetes (e-VitaDM-4; ZODIAC-48)

Steven H. Hendriks, Evelien G.W. van Soldt, Michael van Vugt, Klaas H. Groenier, Yvonne Roelofsen, Angela H. E. M. Maas, Henk J. G. Bilo, Nanne Kleefstra, Kornelis J. J. van Hateren

Eur J Gen Pract. 2017; 23(1): 83–90. Published online 2017 Mar 22. doi: 10.1080/13814788.2017.1292348

PMCID:: PMC5774266

Article PDF–696K

Select item 279519717.

The Lipid Profile and Mortality Risk in Elderly Type 2 Diabetic Patients: A Ten-Year Follow-Up Study (ZODIAC-13)

Kornelis J. J. van Hateren, Gijs W. D. Landman, Nanne Kleefstra, Susan J. J. Logtenberg, Klaas H. Groenier, Adriaan M. Kamper, Sebastiaan T. Houweling, Henk J. G. Bilo

PLoS One. 2009; 4(12): e8464. Published online 2009 Dec 24. doi: 10.1371/journal.pone.0008464

PMCID:: PMC2795197

Article PDF–342K

Select item 378150818.

Copeptin, a Surrogate Marker for Arginine Vasopressin, Is Associated With Cardiovascular and All-Cause Mortality in Patients With Type 2 Diabetes (ZODIAC-31)

Ineke J. Riphagen, Wendy E. Boertien, Alaa Alkhalaf, Nanne Kleefstra, Ron T. Gansevoort, Klaas H. Groenier, Kornelis J.J. van Hateren, Joachim Struck, Gerjan Navis, Henk J.G. Bilo, Stephan J.L. Bakker

Diabetes Care. 2013 Oct; 36(10): 3201–3207. Published online 2013 Sep 14. doi: 10.2337/dc12-2165

PMCID:: PMC3781508

Article PDF–125K

Select item 363185919.

The Midregional Fragment of Pro-A–Type Natriuretic Peptide, Blood Pressure, and Mortality in a Prospective Cohort Study of Patients With Type 2 Diabetes (ZODIAC-25)

Kornelis J.J. van Hateren, Gijs W.D. Landman, Nanne Kleefstra, Klaas H. Groenier, Joachim Struck, Gerjan J. Navis, Stephan J.L. Bakker, Sebastiaan T. Houweling, Klaas van der Meer, Henk J.G. Bilo

Diabetes Care. 2013 May; 36(5): 1347–1352. Published online 2013 Apr 13. doi: 10.2337/dc12-0428

PMCID:: PMC3631859

Article PDF–207K

Select item 553430720.

The Influence of Lunar Phases on Complications in Cataract Surgery: An Analysis of 16,965 Patients

Eva-Maria Faschinger, Pia Veronika Vécsei-Marlovits, Dieter Franz Rabensteiner, Birgit Weingessel

J Ophthalmol. 2017; 2017: 1946527. Published online 2017 Jul 16. doi: 10.1155/2017/1946527

PMCID:: PMC5534307

Article PDF–708K

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Figure 1

Flow chart of inclusion. *For the analyses of the total group of obesity-related cancers, patients diagnosed with a non-sex-specific or sex-specific obesity-related cancer before entering the ZODIAC study were excluded. For the non-sex-specific analysis, only patients with a non-sex-specific cancer before entering the ZODIAC study were excluded. For the sex-specific cancer analysis, only patients with a sex-specific cancer before entering the ZODIAC study were excluded. BMI, body mass index; NKR, the Netherlands Cancer Registry; ZODIAC, Zwolle Outpatient Diabetes project Integrating Available Care.

Association between body mass index and obesity-related cancer risk in men and women with type 2 diabetes in primary care in the Netherlands: a cohort study (ZODIAC-56)

BMJ Open. 2018;8(1):e018859.
Fig. 4

Diagram of the Zodiac in the Iatrosofion Manuscript of the Diskouriou’s Monastery. (By courtesy of Diskouriou’s Monastery library).

Poppies as a sleep aid for infants: The “Hypnos” remedy of Cretan folk medicine

Toxicol Rep. 2021;8:1729-1733.
Figure 7HEXACOPTER GD HX-1100F ZODIAC UAV equipped with a Workswell WIRIW 2nd gen. camera.

Use of aerial thermography to reduce mortality of roe deer fawns before harvest

PeerJ. 2019;7:e6923.
Fig. 1

ZODIAC trial. HR_∗(t) over time in 5 plausible scenarios for the ZODIAC trial: 1) weak correlation (ρ=0.1) and constant hazards for OS and TTP; The remaining scenarios have moderate correlation (ρ=0.5) but with different hazard behavior for OS and TTP: 2) both constant (OS and TTP); 3) constant (OS) and increasing (TTP); 4) constant (OS) and decreasing (TTP); and 5) increasing (OS) and decreasing (TTP)

Using the geometric average hazard ratio in sample size calculation for time-to-event data with composite endpoints

BMC Med Res Methodol. 2021;21:99.