Content of strain A aggregates in whole spinal cords of inoculated and non-inoculated hSOD1G85R Tg mice analyzed with binary epitope mapping. Triangles (triangle), crosses (cross) and circles (unfilled circle) indicate non-symptomatic, symptomatic and end-stage mice, respectively. Blue, violet, green, and red symbols indicate hSOD1G85R Tg mice inoculated with the mouse hSOD1G127X (blue unfilled triangle, blue unfilled cross, blue unfilled circle), human hSOD1G127X I (purple unfilled triangle, purple unfilled cross, purple unfilled circle), mouse control (green unfilled triangle, green unfilled circle) and human control (red unfilled triangle, red unfilled circle) seeds, respectively. Gray indicates non-inoculated mice (gray unfilled triangle, gray unfilled circle) (lifespans minus 102 days, the mean age at which the inoculations took place). The shaded area indicates blank reactions