PMC

Heat map showing the (log₁₀ scaled) reactivity of IgG anti-ganglioside Abs in acute canine polyradiculoneuritis (ACP) patients (n = 25; numbers), local non-neurological controls (n = 19; double letters), and dogs suffering from idiopathic epilepsy (OND, n = 15; single letters). Black corresponds to Ab-negative signals, whereas the intensity of Ab-reactivity increases over blue to green and red, with red corresponding to the strongest signals.

Symptoms in patients younger versus patients older than 50 years. Polyradiculoneuritis was significantly more frequent in patients older than 50 years. In contrast, a meningitic course of the disease was more common in patients under 50 years

Bacterial (Brucella sp.) meningoencephalitis in stranded cetaceans. (A) Severe meningitis in a Brucella sp.-positive striped dolphin (case 30). Brain cortex. HE. 20×. (B) Severe meningomyelitis in a Brucella-sp.-positive striped dolphin (case 30). Spinal cord. HE 4×. (C) Meningomyelitis and polyradiculoneuritis in a Brucella sp.-positive striped dolphin (case 26). Spinal cord. HE 4×. HE. 10×. (D) Vasculitis in a Brucella sp.-positive striped dolphin (case 5). Spinal cord. HE. 20×.

Examples for results obtained in electrophysiologic investigations of acute canine polyradiculoneuritis (ACP) dogs (both dogs exhibited anti-GM2 Abs). (A) Dog 15; (B) dog 16. A1/B1, spontaneous activity in electromyographic assessments of the tibial cranial muscle; A2/B2, motor nerve conduction studies of ulnar (A2) and sciatic/tibial (B2) nerve. Note the reduction of CMAP-amplitude and CMAP dispersion in the second trace of dog A. This dog also exhibited a reduced motor nerve conduction velocity (MNCV; 28.7 m/s). Dog B exhibited a vast reduction of its CMAP amplitude in both traces (<1 mV) with a MNCV (49.1 m/s) at the lower end of the physiological reference rage. Divisions on the abscissa are 2 ms (A2) and 5 ms (B2). Divisions on the ordinate are 1 mV (A2) and 200 µV (B2).