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Items: 1 to 20 of 640

1.
Expression, crystallization and preliminary X-ray analysis of the phosphoribosylglycinamide formyltransferase from Streptococcus mutans
Fangli Zhai, Xiaojuan Liu, Jing Ruan, Jing Li, Zhenlong Liu, Yulin Hu, Shentao Li
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Feb 1; 67(Pt 2): 287–290. Published online 2011 Jan 27. doi: 10.1107/S1744309110053170
PMCID:
PMC3034630
ArticlePDF–243K
2.
Mutations in the Chinese hamster ovary cell GART gene of de novo purine synthesis
Aaron J. Knox, Christine Graham, John Bleskan, Gary Brodsky, David Patterson
Gene. Author manuscript; available in PMC 2010 Jan 15.
Published in final edited form as: Gene. 2009 Jan 15; 429(1-2): 23–30. Published online 2008 Oct 21. doi: 10.1016/j.gene.2008.10.007
PMCID:
PMC2643067
ArticlePDF–891K
3.
Folic Acid-Metabolizing Enzymes Regulate the Antitumor Effect of 5-Fluoro-2′-Deoxyuridine in Colorectal Cancer Cell Lines
Hiroshi Tsukihara, Kenta Tsunekuni, Teiji Takechi
PLoS One. 2016; 11(9): e0163961. Published online 2016 Sep 29. doi: 10.1371/journal.pone.0163961
PMCID:
PMC5042458
ArticlePDF–1.4M
4.
PurN Is Involved in Antibiotic Tolerance and Virulence in Staphylococcus aureus
Qi Peng, Lu Guo, Yu Dong, Tingrui Bao, Huiyuan Wang, Tao Xu, Ying Zhang, Jian Han
Antibiotics (Basel) 2022 Dec; 11(12): 1702. Published online 2022 Nov 25. doi: 10.3390/antibiotics11121702
PMCID:
PMC9774800
ArticlePDF–2.3M
5.
Comparative Genomic Analysis of Haemophilus haemolyticus and Nontypeable Haemophilus influenzae and a New Testing Scheme for Their Discrimination
Fang Hu, Lavanya Rishishwar, Ambily Sivadas, Gabriel J. Mitchell, I. King Jordan, Timothy F. Murphy, Janet R. Gilsdorf, Leonard W. Mayer, Xin Wang
J Clin Microbiol. 2016 Dec; 54(12): 3010–3017. Prepublished online 2016 Oct 5. Published online 2016 Nov 23. doi: 10.1128/JCM.01511-16
PMCID:
PMC5121393
ArticlePDF–1.8M
6.
Multiple purine pathway enzyme activities are encoded at a single genetic locus in Drosophila.
S Henikoff, M A Keene, J S Sloan, J Bleskan, R Hards, D Patterson
Proc Natl Acad Sci U S A. 1986 Feb; 83(3): 720–724. doi: 10.1073/pnas.83.3.720
PMCID:
PMC322936
SummaryPage BrowsePDF–1.2M
7.
Two Drosophila melanogaster mutations block successive steps of de novo purine synthesis.
S Henikoff, D Nash, R Hards, J Bleskan, J F Woolford, F Naguib, D Patterson
Proc Natl Acad Sci U S A. 1986 Jun; 83(11): 3919–3923. doi: 10.1073/pnas.83.11.3919
PMCID:
PMC323636
SummaryPage BrowsePDF–1.0M
8.
Structures of apo and complexed Escherichia coli glycinamide ribonucleotide transformylase.
R J Almassy, C A Janson, C C Kan, Z Hostomska
Proc Natl Acad Sci U S A. 1992 Jul 1; 89(13): 6114–6118. doi: 10.1073/pnas.89.13.6114
PMCID:
PMC49448
SummaryPage BrowsePDF–1.2M
9.
De Novo Purine Nucleotide Biosynthesis Pathway Is Required for Development and Pathogenicity in Magnaporthe oryzae
Meng-Yu Liu, Li-Xiao Sun, Hui Qian, Yun-Ran Zhang, Xue-Ming Zhu, Lin Li, Shuang Liang, Jian-Ping Lu, Fu-Cheng Lin, Xiao-Hong Liu
J Fungi (Basel) 2022 Sep; 8(9): 915. Published online 2022 Aug 29. doi: 10.3390/jof8090915
PMCID:
PMC9502316
ArticlePDF–3.5M
10.
Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations.
D Schild, A J Brake, M C Kiefer, D Young, P J Barr
Proc Natl Acad Sci U S A. 1990 Apr; 87(8): 2916–2920. doi: 10.1073/pnas.87.8.2916
PMCID:
PMC53804
SummaryPage BrowsePDF–1.2M
11.
Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes.
A Gnirke, T S Barnes, D Patterson, D Schild, T Featherstone, M V Olson
EMBO J. 1991 Jul; 10(7): 1629–1634. doi: 10.1002/j.1460-2075.1991.tb07685.x
PMCID:
PMC452831
SummaryPage BrowsePDF–1.3M
12.
Predicting flexible loop regions that interact with ligands: The challenge of accurate scoring
Matthew L. Danielson, Markus A. Lill
Proteins. Author manuscript; available in PMC 2013 Jan 1.
Published in final edited form as: Proteins. 2012 Jan; 80(1): 246–260. Published online 2011 Nov 9. doi: 10.1002/prot.23199
PMCID:
PMC3243024
ArticlePDF–2.0M
13.
De Novo Purine Synthesis in Vegetative Cells and Myxospores of Myxococcus xanthus
Carl A. Westby, Wen-Cherng Tsai
J Bacteriol. 1974 Mar; 117(3): 1099–1107. doi: 10.1128/jb.117.3.1099-1107.1974
PMCID:
PMC246589
SummaryPage BrowsePDF–1.4M
14.
purU, a source of formate for purT-dependent phosphoribosyl-N-formylglycinamide synthesis.
P L Nagy, G M McCorkle, H Zalkin
J Bacteriol. 1993 Nov; 175(21): 7066–7073. doi: 10.1128/jb.175.21.7066-7073.1993
PMCID:
PMC206834
SummaryPage BrowsePDF–1.5M
15.
An Unbiased Peptide-Wide Discovery Approach to Select Mycobacterium tuberculosis Antigens that Target CD8+ T Cell Response During Infection
Mark J. Cayabyab, Lizeng Qin, Suely S. Kashino, Angelo Izzo, Antonio Campos-Neto
Vaccine. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Vaccine. 2013 Oct 1; 31(42): 4834–4840. Published online 2013 Aug 9. doi: 10.1016/j.vaccine.2013.07.077
PMCID:
PMC3778375
ArticlePDF–1.1M
16.
Formyltetrahydrofolate hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli.
P L Nagy, A Marolewski, S J Benkovic, H Zalkin
J Bacteriol. 1995 Mar; 177(5): 1292–1298. doi: 10.1128/jb.177.5.1292-1298.1995
PMCID:
PMC176736
SummaryPDF–278K
17.
Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling
Jingxuan He, Ling-Nan Zou, Vidhi Pareek, Stephen J. Benkovic
J Biol Chem. 2022 May; 298(5): 101853. Published online 2022 Mar 21. doi: 10.1016/j.jbc.2022.101853
PMCID:
PMC9035706
ArticlePDF–1.8M
18.
Methyl Metabolism and the Clock: An Ancient Story With New Perspectives
Jean-Michel Fustin
J Biol Rhythms. 2022 Jun; 37(3): 235–248. Published online 2022 Apr 5. doi: 10.1177/07487304221083507
PMCID:
PMC9160962
ArticlePDF–3.2M
19.
Deciphering molecular mechanisms underlying chemoresistance in relapsed AML patients: towards precision medicine overcoming drug resistance
May Levin, Michal Stark, Yishai Ofran, Yehuda G. Assaraf
Cancer Cell Int. 2021; 21: 53. Published online 2021 Jan 14. doi: 10.1186/s12935-021-01746-w
PMCID:
PMC7809753
ArticlePDF–3.7M
20.
Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway
Yajing Lv, Xiaoshuang Wang, Xiaoyu Li, Guangwei Xu, Yuting Bai, Jiayi Wu, Yongjun Piao, Yi Shi, Rong Xiang, Longlong Wang
PLoS Biol. 2020 Nov; 18(11): e3000872. Published online 2020 Nov 13. doi: 10.1371/journal.pbio.3000872
PMCID:
PMC7688141
ArticlePDF–4.9M

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