PMC

Typical imaging findings for each of the four groups at the level of the carotid bifurcation on CTA, 3D MEDIC and T1wBB, described in Table . The color representation for each of the four groups are the same as in Table . In panel A, in blue color, the arrow indicates a large non-calcified plaque component with signal loss on 3D MEDIC and elevated T1w signal (3DMEDIC + /T1w +). In panel B, in yellow color, the arrow indicates a non-calcified plaque component with no signal loss on 3D MEDIC and elevated T1w signal (3DMEDIC-/T1w +). The dotted arrow indicates a calcification, with high attenuation on CTA, signal loss on 3D MEDIC and signal loss on T1w. In panel C, in green color, the filled arrows on both sides indicate large non-calcified plaque components with signal loss on 3D MEDIC and no elevation of Tw1 signal (MEDIC + /T1w). The dotted arrow on the left side indicate a calcification, with high attenuation on CTA, signal loss on 3D MEDIC and signal loss on T1w on the asymptomatic side (this side was not included in final image analysis). In panel D, in white color, the arrow indicates a small non-calcified plaque without signal loss on 3D MEDIC and no T1w signal elevation (MEDIC-/T1w-)

Fibrillation of the retropatellar cartilage imaged with MEDIC (a) and STIR (b). The chondropathia patellae is better depicted by the STIR-sequence (b). In contrast to the MEDIC the STIR also depicts subchondral bone edema due to the higher cartilage-to-effusion contrast-to-noise ratio (STIR = 197 vs. MEDIC = 32).

MEDIC is freely available from CTD. To obtain the most recent version of MEDIC, use the ‘Downloads’ menu tab. The vocabulary can be downloaded in various formats including CSV, TSV (red circle and inset), XML and OBO. We encourage other databases that use MEDIC to provide a direct link from their disease page to CTD’s equivalent disease page to promote interoperability between databases.

Retropatellar delamination imaged with MEDIC (a) and STIR (b). The delamination is better depicted by the STIR-sequence (b) due to the higher cartilage-to-effusion contrast-to-noise ratio (STIR = 231 vs. MEDIC = 29).