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Select item 29362831.

Antiproliferative effect of D-glucuronyl C5-epimerase in human breast cancer cells

Tatiana Y Prudnikova, Liudmila A Mostovich, Natalia V Domanitskaya, Tatiana V Pavlova, Vladimir I Kashuba, Eugene R Zabarovsky, Elvira V Grigorieva

Cancer Cell Int. 2010; 10: 27. Published online 2010 Aug 19. doi: 10.1186/1475-2867-10-27

PMCID:: PMC2936283

Article PDF–989K

Select item 39376852.

A Novel Unsaturated β-Glucuronyl Hydrolase Involved in Ulvan Degradation Unveils the Versatility of Stereochemistry Requirements in Family GH105

Pi Nyvall Collén, Alexandra Jeudy, Jean-François Sassi, Agnès Groisillier, Mirjam Czjzek, Pedro M. Coutinho, William Helbert

J Biol Chem. 2014 Feb 28; 289(9): 6199–6211. Published online 2014 Jan 9. doi: 10.1074/jbc.M113.537480

PMCID:: PMC3937685

Article PDF–3.6M

Select item 31373993.

D-Glucuronyl C5-epimerase suppresses small-cell lung cancer cell proliferation in vitro and tumour growth in vivo

E V Grigorieva, T Y Prudnikova, N V Domanitskaya, L A Mostovich, T V Pavlova, V I Kashuba, E R Zabarovsky

Br J Cancer. 2011 Jun 28; 105(1): 74–82. Published online 2011 Jun 7. doi: 10.1038/bjc.2011.170

PMCID:: PMC3137399

Article PDF–718K

Select item 37501354.

A Novel Bacterial Enzyme with d-Glucuronyl C5-epimerase Activity

John Raedts, Magnus Lundgren, Servé W. M. Kengen, Jin-Ping Li, John van der Oost

J Biol Chem. 2013 Aug 23; 288(34): 24332–24339. Published online 2013 Jul 3. doi: 10.1074/jbc.M113.476440

PMCID:: PMC3750135

Article PDF–760K

Select item 38927975.

Heterogeneity of d-glucuronyl C5-epimerase expression and epigenetic regulation in prostate cancer

Tatiana Y Prudnikova, Nikolaos Soulitzis, Olesya S Kutsenko, Lyudmila A Mostovich, Klas Haraldson, Ingemar Ernberg, Vladimir I Kashuba, Demetrios A Spandidos, Eugene R Zabarovsky, Elvira V Grigorieva

Cancer Med. 2013 Oct; 2(5): 654–661. Published online 2013 Aug 5. doi: 10.1002/cam4.108

PMCID:: PMC3892797

Article PDF–926K

Select item 30682556.

Occurrence of L-iduronic acid and putative D-glucuronyl C5-epimerases in prokaryotes

John Raedts, Servé W. M. Kengen, John van der Oost

Glycoconj J. 2011; 28(2): 57–66. Published online 2011 Feb 24. doi: 10.1007/s10719-011-9324-7

PMCID:: PMC3068255

Article PDF–853K

Select item 64527397.

Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase

Claire Debarnot, Yoan R. Monneau, Véronique Roig-Zamboni, Vincent Delauzun, Christine Le Narvor, Emeline Richard, Jérôme Hénault, Adeline Goulet, Firas Fadel, Romain R. Vivès, Bernard Priem, David Bonnaffé, Hugues Lortat-Jacob, Yves Bourne

Proc Natl Acad Sci U S A. 2019 Apr 2; 116(14): 6760–6765. Published online 2019 Mar 14. doi: 10.1073/pnas.1818333116

PMCID:: PMC6452739

Article PDF–1.2M

Select item 75816568.

Elucidating the unusual reaction kinetics of D-glucuronyl C5-epimerase

Deepika Vaidyanathan, Elena Paskaleva, Troy Vargason, Xia Ke, Scott A McCallum, Robert J Linhardt, Jonathan S Dordick

Glycobiology. 2020 Nov; 30(11): 847–858. Published online 2020 Apr 18. doi: 10.1093/glycob/cwaa035

PMCID:: PMC7581656

Article PDF–989K

Select item 43352039.

Structural and Functional Study of d-Glucuronyl C5-epimerase

Yi Qin, Jiyuan Ke, Xin Gu, Jianping Fang, Wucheng Wang, Qifei Cong, Jie Li, Jinzhi Tan, Joseph S. Brunzelle, Chenghai Zhang, Yi Jiang, Karsten Melcher, Jin-ping Li, H. Eric Xu, Kan Ding

J Biol Chem. 2015 Feb 20; 290(8): 4620–4630. Published online 2015 Jan 7. doi: 10.1074/jbc.M114.602201

PMCID:: PMC4335203

Article PDF–3.0M

Select item 346945210.

miRNA-218 contributes to the regulation of D-glucuronyl C5-epimerase expression in normal and tumor breast tissues

Tatiana Y. Prudnikova, Luydmila A. Mostovich, Vladimir I. Kashuba, Ingemar Ernberg, Eugene R. Zabarovsky, Elvira V. Grigorieva

Epigenetics. 2012 Oct 1; 7(10): 1109–1114. doi: 10.4161/epi.22103

PMCID:: PMC3469452

Article PDF–626K

Select item 403627511.

Mechanistic Investigations of Unsaturated Glucuronyl Hydrolase from Clostridium perfringens

Seino A. K. Jongkees, Hayoung Yoo, Stephen G. Withers

J Biol Chem. 2014 Apr 18; 289(16): 11385–11395. Published online 2014 Feb 26. doi: 10.1074/jbc.M113.545293

PMCID:: PMC4036275

Article PDF–1.0M

Select item 342728812.

The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer

Luydmila A. Mostovich, Tatiana Y. Prudnikova, Aleksandr G. Kondratov, Natalya V. Gubanova, Olga A. Kharchenko, Olesya S. Kutsenko, Pavel V. Vavilov, Klas Haraldson, Vladimir I. Kashuba, Ingemar Ernberg, Eugene R. Zabarovsky, Elvira V. Grigorieva

Epigenetics. 2012 Aug 1; 7(8): 930–939. doi: 10.4161/epi.21199

PMCID:: PMC3427288

Article PDF–1.4M

Select item 393104013.

Crystal Structure of a Bacterial Unsaturated Glucuronyl Hydrolase with Specificity for Heparin

Yusuke Nakamichi, Bunzo Mikami, Kousaku Murata, Wataru Hashimoto

J Biol Chem. 2014 Feb 21; 289(8): 4787–4797. Published online 2014 Jan 8. doi: 10.1074/jbc.M113.522573

PMCID:: PMC3931040

Article PDF–2.4M

Select item 119892914.

The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the β-catenin–TCF4 pathway

Giancarlo Ghiselli, Amit Agrawal

Biochem J. 2005 Sep 1; 390(Pt 2): 493–499. Prepublished online 2005 Apr 27. Published online 2005 Aug 23. doi: 10.1042/BJ20050152

PMCID:: PMC1198929

Article PDF–435K

Select item 384305315.

Analysis of Drosophila Glucuronyl C5-Epimerase: IMPLICATIONS FOR DEVELOPMENTAL ROLES OF HEPARAN SULFATE SULFATION COMPENSATION AND 2-O-SULFATED GLUCURONIC ACID

Katsufumi Dejima, Masahiko Takemura, Eriko Nakato, Jesse Peterson, Yoshiki Hayashi, Akiko Kinoshita-Toyoda, Hidenao Toyoda, Hiroshi Nakato

J Biol Chem. 2013 Nov 29; 288(48): 34384–34393. Published online 2013 Oct 16. doi: 10.1074/jbc.M113.499269

PMCID:: PMC3843053

Article PDF–2.0M

Select item 480880216.

Functional Analysis of the Glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct Activities towards the O-linked T-antigen

Isabelle Breloy, Tilo Schwientek, Deborah Althoff, Marvin Holz, Tim Koppen, Angelika Krupa, Franz-Georg Hanisch

Biomolecules. 2016 Mar; 6(1): 8. Published online 2016 Jan 6. doi: 10.3390/biom6010008

PMCID:: PMC4808802

Article PDF–4.1M

Select item 683734017.

Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices

Sayoko Oiki, Yusuke Nakamichi, Yukie Maruyama, Bunzo Mikami, Kousaku Murata, Wataru Hashimoto

PLoS One. 2019; 14(11): e0224753. Published online 2019 Nov 7. doi: 10.1371/journal.pone.0224753

PMCID:: PMC6837340

Article PDF–2.6M

Select item 498063218.

Enzyme overexpression – an exercise toward understanding regulation of heparan sulfate biosynthesis

Jianping Fang, Tianyi Song, Ulf Lindahl, Jin-Ping Li

Sci Rep. 2016; 6: 31242. Published online 2016 Aug 11. doi: 10.1038/srep31242

PMCID:: PMC4980632

Article PDF–965K

Select item 754195919.

Novel Hyaluronate Lyase Involved in Pathogenicity of Streptococcus dysgalactiae subsp. equisimilis

Van An Nguyen, Kohei Ogura, Miki Matsue, Norihiko Takemoto, Kanae Mukai, Yukari Nakajima, Thuy Linh Hoang, Yasunori Iwata, Norihiko Sakai, Takashi Wada, Wataru Hashimoto, Shigefumi Okamoto, Hiroshi Ichimura

Front Microbiol. 2020; 11: 552418. Published online 2020 Sep 24. doi: 10.3389/fmicb.2020.552418