dimethylargininase - PMC

Vinitha N. Ragavan, Pramod C. Nair, Natalia Jarzebska, Ramcharan Singh Angom, Luana Ruta, Elisa Bianconi, Silvia Grottelli, Natalia D. Tararova, Daniel Ryazanskiy, Steven R. Lentz, Sara Tommasi, Jens Martens-Lobenhoffer, Toshiko Suzuki-Yamamoto, Masumi Kimoto, Elena Rubets, Sarah Chau, Yingjie Chen, Xinli Hu, Nadine Bernhardt, Peter M. Spieth, Norbert Weiss, Stefan R. Bornstein, Debabrata Mukhopadhyay, Stefanie M. Bode-Böger, Renke Maas, Ying Wang, Antonio Macchiarulo, Arduino A. Mangoni, Barbara Cellini, Roman N. Rodionov

Nat Commun. 2023; 14: 3392. Published online 2023 Jun 9. doi: 10.1038/s41467-023-38467-9

PMCID:: PMC10256801

Abstract Article PDF–2.8M

Select item 70735084.

Intraplatelet L-Arginine-Nitric Oxide Metabolic Pathway: From Discovery to Clinical Implications in Prevention and Treatment of Cardiovascular Disorders

Jakub Gawrys, Damian Gajecki, Ewa Szahidewicz-Krupska, Adrian Doroszko

Oxid Med Cell Longev. 2020; 2020: 1015908. Published online 2020 Mar 3. doi: 10.1155/2020/1015908

PMCID:: PMC7073508

Abstract Article PDF–662K

Select item 60740315.

Dissection, Optimization and Structural Analysis of a Covalent Irreversible DDAH1 Inhibitor

Gayle Burstein-Teitelbaum, Joyce A.V. Er, Arthur F. Monzingo, Alfred Tuley, Walter Fast

Biochemistry. Author manuscript; available in PMC 2019 Jul 31.

Published in final edited form as: Biochemistry. 2018 Jul 31; 57(30): 4574–4582. Published online 2018 Jul 20. doi: 10.1021/acs.biochem.8b00554

PMCID:: PMC6074031

Abstract Article PDF–801K

Select item 36068236.

Development of a dimethylarginine dimethylaminohydrolase (DDAH) assay for high throughput chemical screening

Yohannes T Ghebremariam, Daniel Erlanson, Keisuke Yamada, John P Cooke

J Biomol Screen. Author manuscript; available in PMC 2013 Mar 24.

Published in final edited form as: J Biomol Screen. 2012 Jun; 17(5): 651–661. Published online 2012 Mar 29. doi: 10.1177/1087057112441521

PMCID:: PMC3606823

Abstract Article PDF–1.6M

Select item 27464647.

Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: Toward a targeted polypharmacology to control nitric oxide

Yun Wang, Arthur F. Monzingo, Shougang Hu, Tera H. Schaller, Jon D. Robertus, Walter Fast

Biochemistry. Author manuscript; available in PMC 2010 Sep 15.

Published in final edited form as: Biochemistry. 2009 Sep 15; 48(36): 8624–8635. doi: 10.1021/bi9007098

PMCID:: PMC2746464

Abstract Article PDF–1.3M

Select item 39458198.

Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase

Masooma Rasheed, Christine Richter, Liisa T. Chisty, John Kirkpatrick, Martin Blackledge, Martin R. Webb, Paul C. Driscoll

Biochemistry. 2014 Feb 18; 53(6): 1092–1104. Published online 2014 Jan 31. doi: 10.1021/bi4015924

PMCID:: PMC3945819

Abstract Article PDF–5.3M

Select item 62732169.

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development

Rhys B. Murphy, Sara Tommasi, Benjamin C. Lewis, Arduino A. Mangoni

Molecules. 2016 May; 21(5): 615. Published online 2016 May 11. doi: 10.3390/molecules21050615

PMCID:: PMC6273216

Abstract Article PDF–6.7M

Select item 397582910.

Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators and regulators?

Ben Caplin, James Leiper

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Apr 4.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Jun; 32(6): 1343–1353. Published online 2012 Mar 29. doi: 10.1161/ATVBAHA.112.247726

PMCID:: PMC3975829

Abstract Article PDF–818K

Select item 313759611.

SNOSite: Exploiting Maximal Dependence Decomposition to Identify Cysteine S-Nitrosylation with Substrate Site Specificity

Tzong-Yi Lee, Yi-Ju Chen, Tsung-Cheng Lu, Hsien-Da Huang, Yu-Ju Chen

PLoS One. 2011; 6(7): e21849. Published online 2011 Jul 15. doi: 10.1371/journal.pone.0021849

PMCID:: PMC3137596

Abstract Article PDF–1.6M

Select item 383506712.

DDAH2 mRNA Expression Is Inversely Associated with Some Cardiovascular Risk-Related Features in Healthy Young Adults

Blanca Puchau, Helen Hermana M. Hermsdorff, M. Ángeles Zulet, J. Alfredo Martínez

Dis Markers. 2009; 27(1): 37–44. Published online 2009 Oct 12. doi: 10.3233/DMA-2009-0650

PMCID:: PMC3835067

Summary PDF–165K

Select item 1113643013.

L-arginine regulates asymmetric dimethylarginine metabolism by inhibiting dimethylarginine dimethylaminohydrolase activity in hepatic (HepG2) cells

J. Wang, A. S. Sim, X. L. Wang, D. E. L. Wilcken

Cell Mol Life Sci. 2006 Dec; 63(23): 2838–2846. Published online 2006 Oct 31. doi: 10.1007/s00018-006-6271-8

PMCID:: PMC11136430

Abstract Article PDF–217K

Select item 1116164214.

DDAH-1 maintains endoplasmic reticulum-mitochondria contacts and protects dopaminergic neurons in Parkinson’s disease

Yichen Zhao, Weiwei Shen, Minjie Zhang, Min Guo, Yunxiao Dou, Sida Han, Jintai Yu, Mei Cui, Yanxin Zhao

Cell Death Dis. 2024 Jun; 15(6): 399. Published online 2024 Jun 7. doi: 10.1038/s41419-024-06772-w

PMCID:: PMC11161642

Abstract Article PDF–9.6M

Select item 1087690915.

DDAH1 recruits peroxiredoxin 1 and sulfiredoxin 1 to preserve its activity and regulate intracellular redox homeostasis

Juntao Yuan, Zhuoran Yu, Ping Zhang, Kai Luo, Ying Xu, Ting Lan, Min Zhang, Yingjie Chen, Zhongbing Lu

Redox Biol. 2024 Apr; 70: 103080. Published online 2024 Feb 8. doi: 10.1016/j.redox.2024.103080

PMCID:: PMC10876909

Abstract Article PDF–18M

Select item 613850716.

Proton pump inhibitors and Raynaud's phenomenon: is there a link?

Charles Khouri, Bruno Revol, Jean‐Luc Cracowski, Matthieu Roustit

Br J Clin Pharmacol. 2018 Oct; 84(10): 2443–2444. Published online 2018 Jul 12. doi: 10.1111/bcp.13697

PMCID:: PMC6138507

Article PDF–174K

Select item 1063900717.

Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture

Hanadi Almazroue, Yi Jin, Leif D. Nelin, John C. Barba, 2nd, Avante D. Milton, Jennifer K. Trittmann

Am J Physiol Lung Cell Mol Physiol. 2023 Sep 1; 325(3): L360–L367. Published online 2023 Jul 11. doi: 10.1152/ajplung.00433.2021

PMCID:: PMC10639007

Abstract Article

Select item 971671718.

The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy

Shiyun Wang, Zixuan Deng, Hong Zhang, Rong Zhang, Dandan Yan, Xiaojiao Zheng, Weiping Jia, Cheng Hu

Cardiovasc Diabetol. 2022; 21: 265. Published online 2022 Dec 2. doi: 10.1186/s12933-022-01702-6

PMCID:: PMC9716717

Abstract Article PDF–1.0M

Select item 956911419.

Dimethylarginine dimethylaminohydrolase 1 protects PM_2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Junling Gao, Tong Lei, Hongyun Wang, Kai Luo, Yuanli Wang, Bingqing Cui, Zhuoran Yu, Xiaoqi Hu, Fang Zhang, Yingjie Chen, Wenjun Ding, Zhongbing Lu

Part Fibre Toxicol. 2022; 19: 64. Published online 2022 Oct 14. doi: 10.1186/s12989-022-00505-7

PMCID:: PMC9569114

Abstract Article PDF–16M

Select item 956990320.

Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods

Alena A. Kozlova, Anastasia N. Vaganova, Roman N. Rodionov, Raul R. Gainetdinov, Nadine Bernhardt

Int J Mol Sci. 2022 Oct; 23(19): 11902. Published online 2022 Oct 7. doi: 10.3390/ijms231911902

PMCID:: PMC9569903

Abstract Article PDF–2.4M

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dimethylargininase (268)
PMC
glycogen branching enzyme GbeA, putative [Talaromyces stipitatus ATCC 10500]
glycogen branching enzyme GbeA, putative [Talaromyces stipitatus ATCC 10500]
gi|218722225|gb|EED21643.1||gnl|WGS |cds.TSTA_088790A

Protein
Taf15 TATA-box binding protein associated factor 15 [Mus musculus]
Taf15 TATA-box binding protein associated factor 15 [Mus musculus]
Gene ID:70439

Gene
70439[uid] AND (alive[prop]) (1)
Gene
SDR family NAD(P)-dependent oxidoreductase [Paenibacillus polymyxa]
SDR family NAD(P)-dependent oxidoreductase [Paenibacillus polymyxa]
gi|647226029|ref|WP_025678968.1|

Protein

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