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Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats

J. Lozano-Cuenca, A. González-Hernández, O.A. López-Canales, J.R. Villagrana-Zesati, J.D. Rodríguez-Choreão, R. Morín-Zaragoza, E.F. Castillo-Henkel, J.S. López-Canales

Braz J Med Biol Res. 2017; 50(9): e5765. Published online 2017 Aug 7. doi: 10.1590/1414-431X20175765

PMCID:: PMC5572851

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Possible Mechanisms Involved in the Vasorelaxant Effect Produced by Anorexigenic Drugs in Rat Aortic Rings

Daniela García-Alonso, Dan Morgenstern-Kaplan, Ariel Cohen-Welch, Jair Lozano-Cuenca, Jorge Skiold López-Canales

Med Sci (Basel) 2019 Mar; 7(3): 39. Published online 2019 Feb 27. doi: 10.3390/medsci7030039

PMCID:: PMC6473436

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Drugs and dilated cardiomyopathies: a case/noncase study in the French PharmacoVigilance Database

Guillaume Montastruc, Sylvie Favreliere, Agnès Sommet, Atul Pathak, Maryse Lapeyre-Mestre, Marie-Christine Perault-Pochat, Jean-Louis Montastruc, French Association of Regional PharmacoVigilance Centres

Br J Clin Pharmacol. 2010 Mar; 69(3): 287–294. doi: 10.1111/j.1365-2125.2009.03596.x

PMCID:: PMC2829699

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Neurochemical regulators of food behavior for pharmacological treatment of obesity: current status and future prospects

Gayane Sargis Vardanyan, Hasmik Samvel Harutyunyan, Michail Iosif Aghajanov, Ruben Sargis Vardanyan

Future Med Chem. 2020 Oct; 12(20): 1865–1884. Published online 2020 Oct 12. doi: 10.4155/fmc-2019-0361

PMCID:: PMC7592841

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Pharmacology of stimulants prohibited by the World Anti-Doping Agency (WADA)

J R Docherty

Br J Pharmacol. 2008 Jun; 154(3): 606–622. Published online 2008 May 26. doi: 10.1038/bjp.2008.124

PMCID:: PMC2439527

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Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans: an overview of recent findings

Marcello Serra, Nicola Simola, Alexia E. Pollack, Giulia Costa

Neural Regen Res. 2024 Sep; 19(9): 1908–1918. Published online 2023 Dec 15. doi: 10.4103/1673-5374.390971

PMCID:: PMC11040293

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The Therapeutic Potential of Amphetamine-like Psychostimulants

Bruno Pires, Luana M. Rosendo, Ana Teresa Brinca, Ana Y. Simão, Mário Barroso, Tiago Rosado, Eugenia Gallardo

Life (Basel) 2023 Nov; 13(11): 2180. Published online 2023 Nov 8. doi: 10.3390/life13112180

PMCID:: PMC10671856

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Diffuse Alopecia Areata Associated with Weight-Loss Pills

Sonia Chavez-Alvarez, A. L Villarreal-Alfaro-Lopez, Osvaldo Vazquez-Martinez, Alejandra Villarreal-Martinez

Int J Trichology. 2019 Nov-Dec; 11(6): 236–237. doi: 10.4103/ijt.ijt_101_19

PMCID:: PMC6984043

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Amphetamine increases vascular permeability by modulating endothelial actin cytoskeleton and NO synthase via PAR-1 and VEGF-R

Julia Böttner, Tina Fischer-Schaepmann, Sarah Werner, Sarah Knauth, Heinz-Georg Jahnke, Holger Thiele, Petra Büttner

Sci Rep. 2024; 14: 3596. Published online 2024 Feb 13. doi: 10.1038/s41598-024-53470-w

PMCID:: PMC10864289

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Psychostimulant drugs for cocaine dependence

Xavier Castells, Ruth Cunill, Clara Pérez‐Mañá, Xavier Vidal, Dolors Capellà, Cochrane Drugs and Alcohol Group

Cochrane Database Syst Rev. 2016 Sep; 2016(9): CD007380. Published online 2016 Sep 27. doi: 10.1002/14651858.CD007380.pub4

PMCID:: PMC6457633

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Identification of organic molecules from a structure database using proton and carbon NMR analysis results

Reinhard Dunkel, Xinzi Wu

J Magn Reson. Author manuscript; available in PMC 2008 Sep 1.

Published in final edited form as: J Magn Reson. 2007 Sep; 188(1): 97–110. Published online 2007 Jun 30. doi: 10.1016/j.jmr.2007.06.007

PMCID:: PMC2096635

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Visible-light-induced N-alkylation of anilines with 4-hydroxybutan-2-one

Liya Jiang, Ling Ni, Xinyue Tang, Jonathan B. Baell, Fei Huang, Lanhui Ren

RSC Adv. 2024 Apr 25; 14(20): 14452–14455. Published online 2024 May 1. doi: 10.1039/d4ra01339e

PMCID:: PMC11061780

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Dog and cat exposures to drugs of abuse identified by the California animal health and food safety laboratory system 2013–2023

Sigal Klainbart, Chelsea A. Sykes, Robert H. Poppenga

Front Vet Sci. 2024; 11: 1372614. Published online 2024 Mar 7. doi: 10.3389/fvets.2024.1372614

PMCID:: PMC10954829

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Position statement on nutrition therapy for overweight and obesity: nutrition department of the Brazilian association for the study of obesity and metabolic syndrome (ABESO—2022)

Renata Bressan Pepe, Ana Maria Lottenberg, Clarissa Tamie Hiwatashi Fujiwara, Mônica Beyruti, Dennys Esper Cintra, Roberta Marcondes Machado, Alessandra Rodrigues, Natália Sanchez Oliveira Jensen, Ana Paula Silva Caldas, Ariana Ester Fernandes, Carina Rossoni, Fernanda Mattos, João Henrique Fabiano Motarelli, Josefina Bressan, Juliana Saldanha, Lis Mie Masuzawa Beda, Maria Sílvia Ferrari Lavrador, Mariana Del Bosco, Patrícia Cruz, Poliana Espíndola Correia, Priscila Maximino, Silvia Pereira, Sílvia Leite Faria, Silvia Maria Fraga Piovacari

Diabetol Metab Syndr. 2023; 15: 124. Published online 2023 Jun 9. doi: 10.1186/s13098-023-01037-6

PMCID:: PMC10251611

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Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats

Felipe Patricio, Eliud Morales Dávila, Aleidy Patricio-Martínez, Nayeli Arana Del Carmen, Isabel Martínez, José Aguilera, Jose Manuel Perez-Aguilar, Ilhuicamina Daniel Limón

Front Pharmacol. 2022; 13: 945836. Published online 2022 Sep 2. doi: 10.3389/fphar.2022.945836

PMCID:: PMC9479130

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Endothelium-dependent vasorelaxant effects of praeruptorin a in isolated rat thoracic aorta

Zhenkun Li, Fengrong Zhang, Shicong Wang, Honghe Xiao, Jingyi Wang, Xianyu Li, Hongjun Yang

Bioengineered. 2022; 13(4): 10038–10046. Published online 2022 Apr 13. doi: 10.1080/21655979.2022.2062979

PMCID:: PMC9162007

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Utilizing the DNA Aptamer to Determine Lethal α-Amanitin in Mushroom Samples and Urine by Magnetic Bead-ELISA (MELISA)

Jiale Gao, Nuoya Liu, Xiaomeng Zhang, En Yang, Yuzhu Song, Jinyang Zhang, Qinqin Han

Molecules. 2022 Jan; 27(2): 538. Published online 2022 Jan 15. doi: 10.3390/molecules27020538

PMCID:: PMC8779134

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The incretin/glucagon system as a target for pharmacotherapy of obesity

Stefano Del Prato, Baptist Gallwitz, Jens Juul Holst, Juris J. Meier

Obes Rev. 2022 Feb; 23(2): e13372. Published online 2021 Oct 28. doi: 10.1111/obr.13372

PMCID:: PMC9286339

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Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes

Xuzhong Shen, Xu Chen, Jieping Chen, Yufeng Sun, Zhaoyang Cheng, Zhan Lu

Nat Commun. 2020; 11: 783. Published online 2020 Feb 7. doi: 10.1038/s41467-020-14459-x

PMCID:: PMC7005876

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Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry

Thomas P. Bambauer, Lea Wagmann, Armin A. Weber, Markus R. Meyer

Toxins (Basel) 2020 Nov; 12(11): 671. Published online 2020 Oct 23. doi: 10.3390/toxins12110671

PMCID:: PMC7690657

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PMC Images search for clobenzorex

Figure 1.Representative tracings illustrating the relaxation response produced by the application of clobenzorex and sodium nitroprusside on endothelium-intact and endothelium-denuded phenylephrine-precontracted rat aortic rings. Clobenzorex (A) and sodium nitroprusside (SNP) (C) produced a dose-dependent vasorelaxant response in endothelium-intact phenylephrine-precontracted rat aortic rings. Endothelial denudation blocked the vasorelaxation to clobenzorex (B), but not to SNP (D). Similar results were obtained in all assays (n=8).

Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats

Braz J Med Biol Res. 2017;50(9):e5765.
Figure 2.Pre-incubation with 10–6 M atropine did not modify the vasorelaxation produced by 10–9–10–5 M clobenzorex in phenylephrine (PE)-precontracted rat aortic rings. Data are reported as means±SE of 8 observations.

Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats

Braz J Med Biol Res. 2017;50(9):e5765.
Figure 5.Vasorelaxation produced by 10–9–10–5 M clobenzorex in phenylephrine-precontracted rat aortic rings. Assays were carried out to test the effect of: A, 10–5 M indomethacin; B, 10–5 M clotrimazole; and C, 10–5 M cycloheximide. Data are reported as means±SE of 8 observations.

Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats

Braz J Med Biol Res. 2017;50(9):e5765.
Figure 3.Vasorelaxation produced by 10–9–10–5 M clobenzorex in phenylephrine (PE)-precontracted rat aortic rings. Assays were carried out to test the effect of: A, 10–5 M L-NAME; B, 10–7 M ODQ; and C, 10–6 M KT 5823. Data are reported as means±SE of 8 observations. *P<0.05 vs control (two-way ANOVA).

Possible mechanisms involved in the vasorelaxant effect produced by clobenzorex in aortic segments of rats

Braz J Med Biol Res. 2017;50(9):e5765.