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Select item 106862891.

The 2023 wearable photoplethysmography roadmap

Peter H Charlton, John Allen, Raquel Bailón, Stephanie Baker, Joachim A Behar, Fei Chen, Gari D Clifford, David A Clifton, Harry J Davies, Cheng Ding, Xiaorong Ding, Jessilyn Dunn, Mohamed Elgendi, Munia Ferdoushi, Daniel Franklin, Eduardo Gil, Md Farhad Hassan, Jussi Hernesniemi, Xiao Hu, Nan Ji, Yasser Khan, Spyridon Kontaxis, Ilkka Korhonen, Panicos A Kyriacou, Pablo Laguna, Jesús Lázaro, Chungkeun Lee, Jeremy Levy, Yumin Li, Chengyu Liu, Jing Liu, Lei Lu, Danilo P Mandic, Vaidotas Marozas, Elisa Mejía-Mejía, Ramakrishna Mukkamala, Meir Nitzan, Tania Pereira, Carmen C Y Poon, Jessica C Ramella-Roman, Harri Saarinen, Md Mobashir Hasan Shandhi, Hangsik Shin, Gerard Stansby, Toshiyo Tamura, Antti Vehkaoja, Will Ke Wang, Yuan-Ting Zhang, Ni Zhao, Dingchang Zheng, Tingting Zhu

Physiol Meas. 2023 Nov 1; 44(11): 111001. Published online 2023 Nov 29. doi: 10.1088/1361-6579/acead2

PMCID:: PMC10686289

Abstract Article PDF–5.1M

Select item 107478352.

Physical Noninvasive Attacks on Photoplethysmogram by Computer Controlled Blood Pressure Cuff

Kazuki Yoshida, Ryota Sawano, Masahiro Okamoto, Kazuya Murao, Shuhei Tsuchida, Tsutomu Terada

Sensors (Basel) 2023 Dec; 23(24): 9764. Published online 2023 Dec 11. doi: 10.3390/s23249764

PMCID:: PMC10747835

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Select item 76546583.

Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice

Martina Comelli, Marianna Meo, Daniel O. Cervantes, Emanuele Pizzo, Aaron Plosker, Peter J. Mohler, Thomas J. Hund, Jason T. Jacobson, Olivier Meste, Marcello Rota

Am J Physiol Heart Circ Physiol. 2020 Oct 1; 319(4): H893–H905. Published online 2020 Sep 4. doi: 10.1152/ajpheart.00379.2020

PMCID:: PMC7654658

Abstract Article

Select item 64056724.

β‐Blockers and 1‐Year Postdischarge Mortality for Heart Failure and Reduced Ejection Fraction and Slow Discharge Heart Rate

Jin Joo Park, Hyun‐Ah Park, Hyun‐Jai Cho, Hae‐Young Lee, Kye Hun Kim, Byung‐Su Yoo, Seok‐Min Kang, Sang Hong Baek, Eun‐Seok Jeon, Jae‐Joong Kim, Myeong‐Chan Cho, Shung Chull Chae, Byung‐Hee Oh, Dong‐Ju Choi

J Am Heart Assoc. 2019 Feb 19; 8(4): e011121. Published online 2019 Feb 13. doi: 10.1161/JAHA.118.011121

PMCID:: PMC6405672

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Select item 65842445.

Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation

Ify R. Mordi, Bernadet T. Santema, Mariëlle Kloosterman, Anna-Maria Choy, Michiel Rienstra, Isabelle van Gelder, Stefan D. Anker, John G. Cleland, Kenneth Dickstein, Gerasimos Filippatos, Pim van der Harst, Hans L. Hillege, Marco Metra, Leong L. Ng, Wouter Ouwerkerk, Piotr Ponikowski, Nilesh J. Samani, Dirk J. van Veldhuisen, Aeilko H. Zwinderman, Faiez Zannad, Adriaan A. Voors, Chim C. Lang

Clin Res Cardiol. 2019; 108(7): 797–805. Published online 2019 Jan 4. doi: 10.1007/s00392-018-1409-x

PMCID:: PMC6584244

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Discharge Heart Rate After Hospitalization for Myocardial Infarction and Long‐Term Mortality in 2 US Registries

Venkatesh Alapati, Fengming Tang, Esti Charlap, Paul S. Chan, Paul A. Heidenreich, Philip G. Jones, John A. Spertus, Vankeepuram Srinivas, Jorge R. Kizer

J Am Heart Assoc. 2019 Feb 5; 8(3): e010855. Published online 2019 Jan 29. doi: 10.1161/JAHA.118.010855

PMCID:: PMC6405572

Abstract Article PDF–462K

Select item 67494087.

In-Ear Pulse Rate Measurement: A Valid Alternative to Heart Rate Derived from Electrocardiography?

Stefanie Passler, Niklas Müller, Veit Senner

Sensors (Basel) 2019 Sep; 19(17): 3641. Published online 2019 Aug 21. doi: 10.3390/s19173641

PMCID:: PMC6749408

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Select item 80735458.

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

Alicia D’Souza, Yanwen Wang, Cali Anderson, Annalisa Bucchi, Mirko Baruscotti, Servé Olieslagers, Pietro Mesirca, Anne Berit Johnsen, Svetlana Mastitskaya, Haibo Ni, Yu Zhang, Nicholas Black, Charlotte Cox, Sven Wegner, Beatriz Bano-Otalora, Cheryl Petit, Eleanor Gill, Sunil Jit R.J. Logantha, Halina Dobrzynski, Nick Ashton, George Hart, Rai Zhang, Henggui Zhang, Elizabeth J. Cartwright, Ulrik Wisloff, Matteo E. Mangoni, Paula A. da Costa Martins, Hugh D. Piggins, Dario DiFrancesco, Mark R. Boyett

Heart Rhythm. 2021 May; 18(5): 801–810. doi: 10.1016/j.hrthm.2020.11.026

PMCID:: PMC8073545

Abstract Article

Select item 70454369.

Association of pulse rate with outcomes in heart failure with reduced ejection fraction: a retrospective cohort study

Katherine E. Kurgansky, Petra Schubert, Rachel Parker, Luc Djousse, Jerome B. Riebman, David R. Gagnon, Jacob Joseph

BMC Cardiovasc Disord. 2020; 20: 92. Published online 2020 Feb 26. doi: 10.1186/s12872-020-01384-6

PMCID:: PMC7045436

Abstract Article PDF–923K

Select item 871042610.

Neonatal heart rate variability: a contemporary scoping review of analysis methods and clinical applications

Samantha Latremouille, Justin Lam, Wissam Shalish, Guilherme Sant'Anna

BMJ Open. 2021; 11(12): e055209. Published online 2021 Dec 21. doi: 10.1136/bmjopen-2021-055209

PMCID:: PMC8710426

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Heart Rate at Hospital Discharge in Patients With Heart Failure Is Associated With Mortality and Rehospitalization

Warren K. Laskey, Ihab Alomari, Margueritte Cox, Phillip J. Schulte, Xin Zhao, Adrian F. Hernandez, Paul A. Heidenreich, Zubin J. Eapen, Clyde Yancy, Deepak L. Bhatt, Gregg C. Fonarow, the AHA Get With The Guidelines^®‐Heart Failure Program

J Am Heart Assoc. 2015 Apr; 4(4): e001626. Published online 2015 Apr 22. doi: 10.1161/JAHA.114.001626

PMCID:: PMC4579947

Abstract Article PDF–487K

Select item 1015021112.

Non-canonical role of the sympathetic nervous system in the day–night rhythm in heart rate

Cali Anderson, Gabriella Forte, Wei Hu, Henggui Zhang, Mark R. Boyett, Alicia D'Souza

Philos Trans R Soc Lond B Biol Sci. June 19, 2023; 378(1879): 20220179. Published online May 01, 2023. doi: 10.1098/rstb.2022.0179

PMCID:: PMC10150211

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Select item 680376713.

Heart Rate Correction of the J-to-Tpeak Interval

Katerina Hnatkova, Jose Vicente, Lars Johannesen, Christine Garnett, David G. Strauss, Norman Stockbridge, Marek Malik

Sci Rep. 2019; 9: 15060. Published online 2019 Oct 21. doi: 10.1038/s41598-019-51491-4

PMCID:: PMC6803767

Abstract Article PDF–7.0M

Select item 886981114.

A Real-Time PPG Peak Detection Method for Accurate Determination of Heart Rate during Sinus Rhythm and Cardiac Arrhythmia

Dong Han, Syed Khairul Bashar, Jesús Lázaro, Fahimeh Mohagheghian, Andrew Peitzsch, Nishat Nishita, Eric Ding, Emily L. Dickson, Danielle DiMezza, Jessica Scott, Cody Whitcomb, Timothy P. Fitzgibbons, David D. McManus, Ki H. Chon

Biosensors (Basel) 2022 Feb; 12(2): 82. Published online 2022 Jan 29. doi: 10.3390/bios12020082

PMCID:: PMC8869811

Abstract Article PDF–5.8M

Select item 1042917715.

Heart rate reduction after genetic ablation of L-type Ca_v1.3 channels induces cardioprotection against ischemia-reperfusion injury

Viviana Delgado-Betancourt, Kroekkiat Chinda, Pietro Mesirca, Christian Barrère, Aurélie Covinhes, Laura Gallot, Anne Vincent, Isabelle Bidaud, Sarawut Kumphune, Joël Nargeot, Christophe Piot, Kevin Wickman, Matteo Elia Mangoni, Stéphanie Barrère-Lemaire

Front Cardiovasc Med. 2023; 10: 1134503. Published online 2023 Aug 1. doi: 10.3389/fcvm.2023.1134503

PMCID:: PMC10429177

Abstract Article PDF–4.6M

Select item 749677116.

Influence of an SGLT2 inhibitor, tofogliflozin, on the resting heart rate in relation to adipose tissue insulin resistance

T. Nojima, Y. Matsubayashi, A. Yoshida, H. Suganami, T. Abe, M. Ishizawa, K. Fujihara, S. Tanaka, K. Kaku, H. Sone

Diabet Med. 2020 Aug; 37(8): 1316–1325. Published online 2020 Mar 17. doi: 10.1111/dme.14279

PMCID:: PMC7496771

Abstract Article PDF–495K

Select item 1006235817.

Accuracy of continuous photoplethysmography-based 1 min mean heart rate assessment during atrial fibrillation

Astrid N L Hermans, Jonas L Isaksen*, Monika Gawalko, Nikki A H A Pluymaekers, Rachel M J van der Velden, Hilco Snippe, Stijn Evens, Glenn De Witte, Justin G L M Luermans, Martin Manninger, Joost Lumens, Jørgen K Kanters, Dominik Linz

Europace. 2023 Mar; 25(3): 835–844. Published online 2023 Feb 7. doi: 10.1093/europace/euad011

PMCID:: PMC10062358

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Select item 547473218.

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Ilja M. Nolte, M. Loretto Munoz, Vinicius Tragante, Azmeraw T. Amare, Rick Jansen, Ahmad Vaez, Benedikt von der Heyde, Christy L. Avery, Joshua C. Bis, Bram Dierckx, Jenny van Dongen, Stephanie M. Gogarten, Philippe Goyette, Jussi Hernesniemi, Ville Huikari, Shih-Jen Hwang, Deepali Jaju, Kathleen F. Kerr, Alexander Kluttig, Bouwe P. Krijthe, Jitender Kumar, Sander W. van der Laan, Leo-Pekka Lyytikäinen, Adam X. Maihofer, Arpi Minassian, Peter J. van der Most, Martina Müller-Nurasyid, Michel Nivard, Erika Salvi, James D. Stewart, Julian F. Thayer, Niek Verweij, Andrew Wong, Delilah Zabaneh, Mohammad H. Zafarmand, Abdel Abdellaoui, Sulayma Albarwani, Christine Albert, Alvaro Alonso, Foram Ashar, Juha Auvinen, Tomas Axelsson, Dewleen G. Baker, Paul I. W. de Bakker, Matteo Barcella, Riad Bayoumi, Rob J. Bieringa, Dorret Boomsma, Gabrielle Boucher, Annie R. Britton, Ingrid Christophersen, Andrea Dietrich, George B. Ehret, Patrick T. Ellinor, Markku Eskola, Janine F. Felix, John S. Floras, Oscar H. Franco, Peter Friberg, Maaike G. J. Gademan, Mark A. Geyer, Vilmantas Giedraitis, Catharina A. Hartman, Daiane Hemerich, Albert Hofman, Jouke-Jan Hottenga, Heikki Huikuri, Nina Hutri-Kähönen, Xavier Jouven, Juhani Junttila, Markus Juonala, Antti M. Kiviniemi, Jan A. Kors, Meena Kumari, Tatiana Kuznetsova, Cathy C. Laurie, Joop D. Lefrandt, Yong Li, Yun Li, Duanping Liao, Marian C. Limacher, Henry J. Lin, Cecilia M. Lindgren, Steven A. Lubitz, Anubha Mahajan, Barbara McKnight, Henriette Meyer zu Schwabedissen, Yuri Milaneschi, Nina Mononen, Andrew P. Morris, Mike A. Nalls, Gerjan Navis, Melanie Neijts, Kjell Nikus, Kari E. North, Daniel T. O'Connor, Johan Ormel, Siegfried Perz, Annette Peters, Bruce M. Psaty, Olli T. Raitakari, Victoria B. Risbrough, Moritz F. Sinner, David Siscovick, Johannes H. Smit, Nicholas L. Smith, Elsayed Z. Soliman, Nona Sotoodehnia, Jan A. Staessen, Phyllis K. Stein, Adrienne M. Stilp, Katarzyna Stolarz-Skrzypek, Konstantin Strauch, Johan Sundström, Cees A. Swenne, Ann-Christine Syvänen, Jean-Claude Tardif, Kent D. Taylor, Alexander Teumer, Timothy A. Thornton, Lesley E. Tinker, André G. Uitterlinden, Jessica van Setten, Andreas Voss, Melanie Waldenberger, Kirk C. Wilhelmsen, Gonneke Willemsen, Quenna Wong, Zhu-Ming Zhang, Alan B. Zonderman, Daniele Cusi, Michele K. Evans, Halina K. Greiser, Pim van der Harst, Mohammad Hassan, Erik Ingelsson, Marjo-Riitta Järvelin, Stefan Kääb, Mika Kähönen, Mika Kivimaki, Charles Kooperberg, Diana Kuh, Terho Lehtimäki, Lars Lind, Caroline M. Nievergelt, Chris J. O'Donnell, Albertine J. Oldehinkel, Brenda Penninx, Alexander P. Reiner, Harriëtte Riese, Arie M. van Roon, John D. Rioux, Jerome I. Rotter, Tamar Sofer, Bruno H. Stricker, Henning Tiemeier, Tanja G. M. Vrijkotte, Folkert W. Asselbergs, Bianca J. J. M. Brundel, Susan R. Heckbert, Eric A. Whitsel, Marcel den Hoed, Harold Snieder, Eco J. C. de Geus

Nat Commun. 2017; 8: 15805. Published online 2017 Jun 14. doi: 10.1038/ncomms15805

Correction in:: Nat Commun. 2017; 8: 16140.

PMCID:: PMC5474732

Abstract Article PDF–592K

Select item 511802419.

Advances in the management of heart failure: the role of ivabradine

Ursula Müller-Werdan, Georg Stöckl, Karl Werdan

Vasc Health Risk Manag. 2016; 12: 453–470. Published online 2016 Nov 17. doi: 10.2147/VHRM.S90383

PMCID:: PMC5118024

Abstract Article PDF–576K

Select item 690727520.

Extracting physiological information in experimental biology via Eulerian video magnification

Henrik Lauridsen, Selina Gonzales, Daniela Hedwig, Kathryn L. Perrin, Catherine J. A. Williams, Peter H. Wrege, Mads F. Bertelsen, Michael Pedersen, Jonathan T. Butcher

BMC Biol. 2019; 17: 103. Published online 2019 Dec 12. doi: 10.1186/s12915-019-0716-7

PMCID:: PMC6907275

Abstract Article PDF–18M

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PMC Images search for channel pulse【通信】

FIGURE 3

Gating currents of various channel constructs. (A) Gating current of a K⁺ channel with four eGFP molecules per channel (KG1) and a Na⁺ channel with three eGFP molecules per channel. Because of the higher expression level of K⁺ channels, the corresponding gating current is approximately six times larger in amplitude than that of the Na⁺ channel. Considering the slower kinetics of K⁺ channels, the charge is ≃20 times larger. Pulse protocols: For KG1, holding potential is −100 mV; depolarizing pulse is from −100 to + 60 mV; and hyperpolarizing pulse is from −150 to −180 mV. For NaG3, holding potential is −100 mV; depolarizing pulse is from −100 to + 65 mV; and hyperpolarizing pulse is from −120 to −150 mV. (B) Gating currents of K⁺ channels with eight and twelve eGFP molecules per channel (KG2 and KG3). Both channel constructs are still fully functional despite the insertion of eight and twelve eGFP molecules per channel, respectively. Pulse protocols were for both KG2 and KG3: Holding potential is −100 mV, depolarizing pulse is from −100 to + 60 mV, and hyperpolarizing pulse is from −150 to −180 mV. All applied pulses are sufficient to collect the full gating charge.

More Gating Charges are Needed to Open a Shaker K+ Channel than are Needed to Open an rBIIA Na+ Channel

Biophys J. 2008 Aug 1;95(3):1165-1175.
Fig. 4

Multi-wavelength operation. a Multi-wavelength operation of the photonic–phononic memory for three different laser wavelengths λ for the data pulses (thin lines) (blue curve: 1549 nm, green curve: 1551.3 nm, red curve: 1552.9 nm). The efficiency of the memory remains the same (thick lines). The Brillouin frequency shift Ω was adjusted to 7.75 GHz, 7.74 GHz and 7.73 GHz, respectively. b Phase-matching condition for two data pulses and one write pulse phase-matched to data pulse 1 (corresponds to measurement c, d). The data pulse 2 is not phase-matched and therefore not affected by the write pulse 1. c Storage and retrieval of data pulse 1 (blue and red curve, respectively) while data pulse 2 (d) in a separate channel (100 GHz away from channel 1) is unaffected (blue dashed line: channel 1 off; red line: channel 1 stored and retrieved). e Phase-matching condition for two separate read pulses with data pulse 1 (corresponds to measurement f, g). One can see that read pulse 2 cannot readout phonon 1. f Shows the writing and retrieving of a data pulse (blue and red curve, respectively) in channel 1 while at the same time no readout pulse can be seen in channel 2 (g; blue dashed line: channel 1 off; red line: channel 1 stored and retrieved). h Phase-matching condition for two channels operating at two different wavelengths. i Storage and retrieval of data in channel 1 while simultaneously storing and retrieving data in channel 2 (j) (blue and red curve, respectively). For comparison the storage and retrieval of only channel 2 is depicted by the dashed orange line in j. Note: the difference in the noise floor between channel 1 and channel 2 is caused by the different noise properties of the two different photodiodes

A chip-integrated coherent photonic-phononic memory

Nat Commun. 2017;8:574.
Figure 5

Automated RF pulse calibrations at four resonance frequencies using protons of waters on two channels of the RF probe. The plots are shown as they appear in the Prospa software (1PulseDurationSweep sequence) in the magnitude mode. a) ¹³C channel calibration at 74 kHz. First, proton 180° pulse duration is determined first at ~250 μs corresponding to first “null point” of the nutation curve. ¹³C 90° pulse duration is computed by diving proton 180° pulse duration by 2 and multiplying it by the γ_1H/γ_13C and resulting in ~950 μs value. b) ¹³C channel calibration at 64 kHz. First, proton 180° pulse duration is determined first at ~480 μs corresponding to first “null point” of the nutation curve. ¹³C 90° pulse duration is computed by diving proton 180° pulse duration by 2 and multiplying it by the γ_1H/γ_13C and resulting in ~490 μs value. c) ¹H channel calibration at 222 kHz. Proton 180° pulse duration is determined at 132 μs corresponding to first “null point” of the nutation curve. d) ¹H channel calibration at 254 kHz. Proton 180° pulse duration is determined at 245 μs corresponding to first “null point” of the nutation curve.

A Pulse Programmable Parahydrogen Polarizer Using a Tunable Electromagnet and Dual Channel NMR Spectrometer

J Magn Reson. ;284:115-124.
Figure 1

Pulse Pal is a programmable pulse train generator. (A) Pulse Pal front view, illustrating front panel features. 1: High contrast oLED screen permits programming with thumb joystick for stand-alone use. 2: Custom laser-cut acrylic enclosure. 3: Two optically isolated digital trigger channels. 4: Thumb joystick. 5: Rack-mount wing. 6: Channel activity indicators illuminate when channel voltage is not the set resting voltage (i.e., during a pulse). 7: Each of four analog output channels can be programmed with independent pulse trains and linked to either trigger channel. (B–E) Example pulse trains in black, acquired with an oscilloscope (see methods). Trigger voltage traces are shown in red. (B) A Pulse Pal output channel configured to deliver a train of 5 V, 100 µs square pulses with 200 µs intervals. (C) A train of biphasic +/−5 V 100 µs pulses, gated programmatically to produce pulse bursts. Trigger channel mode set to “toggle” aborts the ongoing pulse train in mid-burst when a second pulse arrives. (D) A train of 500 µs pulses with custom onset times and voltages. Pulses with consecutive onset times merge to form more complex waveforms (right). (E) A train of consecutive 100 µs pulses, whose voltages and onset times were configured to generate one period of a sine waveform. The output channel uses “loop mode”, to repeat the sine waveform until a parametrically specified pulse train end. The trigger channel mode was set to “pulse gated” mode, to abort the pulse train when its voltage returned low.

A low-cost programmable pulse generator for physiology and behavior

Front Neuroeng. 2014;7:43.