asquith - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 1681

<< First< Prev

Page of 85

Next >Last >>

Showing results for asquith. Your search for asquish【科技】 retrieved no results.

Select item 54723251.

HIV-1 adaptation to NK cell-mediated immune pressure

Marjet Elemans, Lies Boelen, Michael Rasmussen, Søren Buus, Becca Asquith

PLoS Pathog. 2017 Jun; 13(6): e1006361. Published online 2017 Jun 5. doi: 10.1371/journal.ppat.1006361

PMCID:: PMC5472325

Article PDF–3.3M

Select item 15602682.

Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE)

Becca Asquith, Christophe Debacq, Arnaud Florins, Nicolas Gillet, Teresa Sanchez-Alcaraz, Angelina Mosley, Luc Willems

Proc Biol Sci. 2006 May 7; 273(1590): 1165–1171. Published online 2006 Jan 31. doi: 10.1098/rspb.2005.3432

PMCID:: PMC1560268

Article PDF–380K

Select item 18510583.

In vivo CD8⁺ T cell control of immunodeficiency virus infection in humans and macaques

Becca Asquith, Angela R. McLean

Proc Natl Acad Sci U S A. 2007 Apr 10; 104(15): 6365–6370. Published online 2007 Apr 2. doi: 10.1073/pnas.0700666104

PMCID:: PMC1851058

Article PDF–284K

Select item 18618534.

In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection

Becca Asquith, Yan Zhang, Angelina J. Mosley, Catherine M. de Lara, Diana L. Wallace, Andrew Worth, Lambrini Kaftantzi, Kiran Meekings, George E. Griffin, Yuetsu Tanaka, David F. Tough, Peter C. Beverley, Graham P. Taylor, Derek C. Macallan, Charles R. M. Bangham

Proc Natl Acad Sci U S A. 2007 May 8; 104(19): 8035–8040. Published online 2007 May 1. doi: 10.1073/pnas.0608832104

PMCID:: PMC1861853

Article PDF–336K

Select item 29161385.

An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer

Mark Asquith, Fiona Powrie

J Exp Med. 2010 Aug 2; 207(8): 1573–1577. doi: 10.1084/jem.20101330

PMCID:: PMC2916138

Article PDF–1.2M

Select item 102667736.

KIR-HLA interactions extend human CD8⁺ T cell lifespan in vivo

Yan Zhang, Ada W.C. Yan, Lies Boelen, Linda Hadcocks, Arafa Salam, Daniel Padrosa Gispert, Loiza Spanos, Laura Mora Bitria, Neda Nemat-Gorgani, James A. Traherne, Chrissy Roberts, Danai Koftori, Graham P. Taylor, Daniel Forton, Paul J. Norman, Steven G.E. Marsh, Robert Busch, Derek C. Macallan, Becca Asquith

J Clin Invest. 2023 Jun 15; 133(12): e169496. Published online 2023 Jun 15. doi: 10.1172/JCI169496

PMCID:: PMC10266773

Article PDF–3.0M

Select item 100490217.

Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles

Andrew A. Bieberich, Christopher R. M. Asquith

Int J Mol Sci. 2023 Mar; 24(6): 5088. Published online 2023 Mar 7. doi: 10.3390/ijms24065088

PMCID:: PMC10049021

Article PDF–1.2M

Select item 107934588.

Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships

Christopher R. M. Asquith, Michael P. East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, Carrow I. Wells, Alison D. Axtman, David H. Drewry, Graham J. Tizzard, Antti Poso, Timothy M. Willson, Gary L. Johnson

Version 1. bioRxiv. Preprint. 2023 Dec 28. doi: 10.1101/2023.12.28.573261

Published in:: Eur J Med Chem. 2024 Apr 2; 271: 116357.

PMCID:: PMC10793458

Article PDF–2.6M

Select item 92331419.

Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype

Christopher R. M. Asquith, Louisa Temme, Michael P. East, Tuomo Laitinen, Julie Pickett, Frank E. Kwarcinski, Parvathi Sinha, Carrow I. Wells, Gary L. Johnson, Reena Zutshi, David H. Drewry

ChemMedChem. Author manuscript; available in PMC 2023 Jun 20.

Published in final edited form as: ChemMedChem. 2022 Jun 20; 17(12): e202200161. Published online 2022 May 9. doi: 10.1002/cmdc.202200161

PMCID:: PMC9233141

Article PDF–1.2M

Select item 851305810.

Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors

Andreas S. Kalogirou, Michael P. East, Tuomo Laitinen, Chad D. Torrice, Kaitlyn A. Maffuid, David H. Drewry, Panayiotis A. Koutentis, Gary L. Johnson, Daniel J. Crona, Christopher R. M. Asquith

Molecules. 2021 Oct; 26(19): 5911. Published online 2021 Sep 29. doi: 10.3390/molecules26195911

PMCID:: PMC8513058

Article PDF–6.3M

Select item 752400711.

The relative contributions of infectious and mitotic spread to HTLV-1 persistence

Daniel J. Laydon, Vikram Sunkara, Lies Boelen, Charles R. M. Bangham, Becca Asquith

PLoS Comput Biol. 2020 Sep; 16(9): e1007470. Published online 2020 Sep 17. doi: 10.1371/journal.pcbi.1007470

PMCID:: PMC7524007

Article PDF–1.9M

Select item 740044612.

Antimicrobial and Antifungal Activity of Rare Substituted 1,2,3-Thiaselenazoles and Corresponding Matched Pair 1,2,3-Dithiazoles

Tuomo Laitinen, Ilia V. Baranovsky, Lidia S. Konstantinova, Antti Poso, Oleg A. Rakitin, Christopher R. M. Asquith

Antibiotics (Basel) 2020 Jul; 9(7): 369. Published online 2020 Jul 1. doi: 10.3390/antibiotics9070369

PMCID:: PMC7400446

Article PDF–4.7M

Select item 715655013.

The Rules of Human T Cell Fate in vivo

Pedro Costa del Amo, Bisrat Debebe, Milad Razavi-Mohseni, Shinji Nakaoka, Andrew Worth, Diana Wallace, Peter Beverley, Derek Macallan, Becca Asquith

Front Immunol. 2020; 11: 573. Published online 2020 Apr 8. doi: 10.3389/fimmu.2020.00573

PMCID:: PMC7156550

Article PDF–2.1M

Select item 562315114.

Intestinal metabolites are profoundly altered in the context of HLA-B27 expression and functionally modulate disease in a rat model of spondyloarthropathy

Mark Asquith, Sean Davin, Patrick Stauffer, Claire Michell, Cathleen Janowitz, Phoebe Lin, Joe Ensign-Lewis, Jason M. Kinchen, Dennis R Koop, James T. Rosenbaum

Arthritis Rheumatol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Arthritis Rheumatol. 2017 Oct; 69(10): 1984–1995. Published online 2017 Aug 31. doi: 10.1002/art.40183

PMCID:: PMC5623151

Article PDF–1.6M

Select item 696376615.

Synthesis and Identification of Pentathiepin-Based Inhibitors of Sporothrix brasiliensis

Christopher R. M. Asquith, Ana C. S. Machado, Luisa H. M. de Miranda, Lidia S. Konstantinova, Rodrigo Almeida-Paes, Oleg A. Rakitin, Sandro A. Pereira

Antibiotics (Basel) 2019 Dec; 8(4): 249. Published online 2019 Dec 3. doi: 10.3390/antibiotics8040249

PMCID:: PMC6963766

Article PDF–2.8M

Select item 724614516.

A Preliminary Report on Interleukin-22, GM-CSF, and IL-17F in the pathogenesis of acute anterior uveitis

Jerry Chien-Chieh Huang, Matthew Schleisman, Dongseok Choi, Claire Mitchell, Lindsey Watson, Mark Asquith, James T. Rosenbaum

Ocul Immunol Inflamm. Author manuscript; available in PMC 2022 Apr 3.

Published in final edited form as: Ocul Immunol Inflamm. 2021 Apr 3; 29(3): 558–565. Published online 2019 Nov 25. doi: 10.1080/09273948.2019.1686156

PMCID:: PMC7246145

Article PDF–614K

Select item 601913417.

1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors

Christopher R. M. Asquith, Paulo H. Godoi, Rafael M. Couñago, Tuomo Laitinen, John W. Scott, Christopher G. Langendorf, Jonathan S. Oakhill, David H. Drewry, William J. Zuercher, Panayiotis A. Koutentis, Timothy M. Willson, Andreas S. Kalogirou

Molecules. 2018 May; 23(5): 1221. Published online 2018 May 19. doi: 10.3390/molecules23051221