Masoprocol - PMC

Madhurima Singh, Stefanie Bittner, Yihang Li, Alex Bittner, Lu Han, Yuan Cortez, Mohammed Inayathullah, Zeeshan Arif, Ramakrishnan Parthasarathi, Jayakumar Rajadas, Wen‐Jun Shen, Mark R Nicolls, Fredric B Kraemer, Salman Azhar

Br J Pharmacol. 2019 Feb; 176(3): 369–385. Published online 2018 Dec 10. doi: 10.1111/bph.14528

PMCID:: PMC6329620

Article PDF–1.6M

Select item 26956753.

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

Randy Strong, Richard A. Miller, Clinton M. Astle, Robert A. Floyd, Kevin Flurkey, Kenneth L. Hensley, Martin A. Javors, Christiaan Leeuwenburgh, James F. Nelson, Ennio Ongini, Nancy L. Nadon, Huber R. Warner, David E. Harrison

Aging Cell. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Aging Cell. 2008 Oct; 7(5): 641–650. doi: 10.1111/j.1474-9726.2008.00414.x

PMCID:: PMC2695675

Article PDF–1.0M

Select item 71302064.

Subject Index to Volumes 86-95

Gastroenterology. 1989 May; 96(5): 95–210. Published online 2016 Aug 12. doi: 10.1016/S0016-5085(89)80008-3

PMCID:: PMC7130206

Abstract PDF–11M

Select item 72272405.

Facile synthesis and nanoscale features of a nanostructured nordihydroguaiaretic acid analog for therapeutic applications

Geraldine Sandana Mala John, Veena Kumari Vuttaradhi, Satoru Takeuchi, Ravi Shankar Pitani, Ganesh Venkatraman, Suresh Kumar Rayala

J Nanobiotechnology. 2020; 18: 74. Published online 2020 May 14. doi: 10.1186/s12951-020-00628-z

PMCID:: PMC7227240

Article PDF–1.8M

Select item 72738096.

Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH)

Lu Han, Stefanie Bittner, Dachuan Dong, Yuan Cortez, Hunter Dulay, Sara Arshad, Wen-Jun Shen, Fredric B. Kraemer, Salman Az har

Mol Cell Endocrinol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Mol Cell Endocrinol. 2019 Dec 1; 498: 110538. Published online 2019 Aug 12. doi: 10.1016/j.mce.2019.110538

PMCID:: PMC7273809

Article PDF–4.2M

Select item 44024807.

Nordihydroguaiaretic Acid Disrupts the Antioxidant Ability of Helicobacter pylori through the Repression of SodB Activity In Vitro

Hitoshi Tsugawa, Hideki Mori, Juntaro Matsuzaki, Tatsuhiro Masaoka, Tasuku Hirayama, Hideko Nagasawa, Yasubumi Sakakibara, Makoto Suematsu, Hidekazu Suzuki

Biomed Res Int. 2015; 2015: 734548. Published online 2015 Apr 6. doi: 10.1155/2015/734548

PMCID:: PMC4402480

Article PDF–953K

Select item 30011068.

Nordihydroguaiaretic Acid Inhibits Insulin-Like Growth Factor Signaling, Growth, and Survival in Human Neuroblastoma Cells

Gary E. Meyer, Louis Chesler, Dandan Liu, Karissa Gable, Betty A. Maddux, David D. Goldenberg, Jack F. Youngren, Ira D. Goldfine, William A. Weiss, Katherine K. Matthay, Stephen M. Rosenthal

J Cell Biochem. Author manuscript; available in PMC 2010 Dec 11.

Published in final edited form as: J Cell Biochem. 2007 Dec 15; 102(6): 1529–1541. doi: 10.1002/jcb.21373

PMCID:: PMC3001106

Article PDF–1.3M

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Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis

Haiyan Zhang, Yihang Li, Jie Hu, Wen-Jun Shen, Madhurima Singh, Xiaoming Hou, Alex Bittner, Stefanie Bittner, Yuan Cortez, Juveria Tabassum, Fredric B. Kraemer, Salman Azhar

PLoS One. 2015; 10(9): e0138203. Published online 2015 Sep 22. doi: 10.1371/journal.pone.0138203

PMCID:: PMC4578927

Article PDF–1.4M

Select item 274592410.

Nordihydroguaiaretic Acid Inhibits an Activated FGFR3 Mutant, and Blocks Downstream Signaling in Multiple Myeloma Cells

April N. Meyer, Christopher W. McAndrew, Daniel J. Donoghue

Cancer Res. Author manuscript; available in PMC 2009 Sep 17.

Published in final edited form as: Cancer Res. 2008 Sep 15; 68(18): 7362–7370. doi: 10.1158/0008-5472.CAN-08-0575

PMCID:: PMC2745924

Article PDF–3.4M

Select item 395493911.

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

David E Harrison, Randy Strong, David B Allison, Bruce N Ames, Clinton M Astle, Hani Atamna, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, Nancy L Nadon, James F Nelson, Scott Pletcher, James W Simpkins, Daniel Smith, J Erby Wilkinson, Richard A Miller

Aging Cell. 2014 Apr; 13(2): 273–282. Published online 2013 Nov 19. doi: 10.1111/acel.12170

PMCID:: PMC3954939

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Select item 354363712.

Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways

Haiyan Zhang, Wen-Jun Shen, Yuan Cortez, Fredric B. Kraemer, Salman Azhar

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1): G72–G86. Published online 2012 Oct 25. doi: 10.1152/ajpgi.00328.2012

PMCID:: PMC3543637

Article

Select item 591945513.

Opposing Effects of Indomethacin and Nordihydroguaiaretic Acid on Macrophage Function and Tumor Growth

Michihiro Suzuki, Jey Li, Toshio Asakura, Kazuhiko Arai

Jpn J Cancer Res. 1994 Mar; 85(3): 306–314. doi: 10.1111/j.1349-7006.1994.tb02098.x

PMCID:: PMC5919455

Article PDF–493K

Select item 591897914.

Anti‐promoting Effect of Nordihydroguaiaretic Acid on N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine and Sodium Saccharin‐induced Rat Urinary Bladder Carcinogenesis

Akinori Yu, Takayuki Hashimura, Yasunori Nishio, Hiroshi Kanamaru, Shigeki Fukuzawa, Osamu Yoshida

Jpn J Cancer Res. 1992 Sep; 83(9): 944–948. doi: 10.1111/j.1349-7006.1992.tb02005.x

PMCID:: PMC5918979

Article PDF–290K

Select item 900288715.

Assessing Nordihydroguaiaretic Acid Therapeutic Effect for Glioblastoma Multiforme

Felicia S. Manciu, Jose Guerrero, Kevin E. Bennet, Su-Youne Chang, Masum Rahman, Lizbeth V. Martinez Lopez, Siobhan Chantigian, Mariana Castellanos, Marian Manciu

Sensors (Basel) 2022 Apr; 22(7): 2643. Published online 2022 Mar 30. doi: 10.3390/s22072643

PMCID:: PMC9002887

Article PDF–1.6M

Select item 803835016.

Nordihydroguaiaretic Acid as a Novel Substrate and Inhibitor of Catechol O-Methyltransferase Modulates 4-Hydroxyestradiol-Induced Cyto- and Genotoxicity in MCF-7 Cells

Jin-Hee Kim, Jimin Lee, Hyesoo Jeong, Mi Seo Bang, Jin-Hyun Jeong, Minsun Chang

Molecules. 2021 Apr; 26(7): 2060. Published online 2021 Apr 3. doi: 10.3390/molecules26072060

PMCID:: PMC8038350

Article PDF–1.5M

Select item 639349117.

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity

Malcolm J. Daniels, J. Brucker Nourse, Jr., Hanna Kim, Valerio Sainati, Marco Schiavina, Maria Grazia Murrali, Buyan Pan, John J. Ferrie, Conor M. Haney, Rani Moons, Neal S. Gould, Antonino Natalello, Rita Grandori, Frank Sobott, E. James Petersson, Elizabeth Rhoades, Roberta Pierattelli, Isabella Felli, Vladimir N. Uversky, Kim A. Caldwell, Guy A. Caldwell, Edward S. Krol, Harry Ischiropoulos

Sci Rep. 2019; 9: 2937. Published online 2019 Feb 27. doi: 10.1038/s41598-019-39480-z

PMCID:: PMC6393491

Article PDF–5.3M

Select item 774793418.

Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products

Nathaniel C. Gilbert, Jana Gerstmeier, Erin E. Schexnaydre, Friedemann Börner, Ulrike Garscha, David B. Neau, Oliver Werz, Marcia E. Newcomer

Nat Chem Biol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Nat Chem Biol. 2020 Jul; 16(7): 783–790. Published online 2020 May 11. doi: 10.1038/s41589-020-0544-7

PMCID:: PMC7747934

Article PDF–981K

Select item 865927019.

The Polyphenols α-Mangostin and Nordihydroguaiaretic Acid Induce Oxidative Stress, Cell Cycle Arrest, and Apoptosis in a Cellular Model of Medulloblastoma

Alberto Rojas-Ochoa, Emilio J. Córdova, Adela Carrillo-García, Marcela Lizano, José Pedraza-Chaverri, Nelly Patiño, Alfredo Cruz-Gregorio, Norma Osnaya

Molecules. 2021 Dec; 26(23): 7230. Published online 2021 Nov 29. doi: 10.3390/molecules26237230

PMCID:: PMC8659270

Article PDF–2.0M

Select item 225349320.

Inhibition of IGF-1R and Lipoxygenase by Nordihydroguaiaretic Acid (NDGA) Analogs

Joseph E. Blecha, Marc O. Anderson, Jennifer M. Chow, Christle C. Guevarra, Celia Pender, Cristina Penaranda, Marianna Zavodovskaya, Jack F. Youngren, Clifford E. Berkman

Bioorg Med Chem Lett. Author manuscript; available in PMC 2008 Jul 15.

Published in final edited form as: Bioorg Med Chem Lett. 2007 Jul 15; 17(14): 4026–4029. Published online 2007 Apr 29. doi: 10.1016/j.bmcl.2007.04.092

PMCID:: PMC2253493

Article PDF–485K

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28.1

Comparison 28 Masoprocol versus placebo, Outcome 1 Global improvement indices‐cured.

Interventions for actinic keratoses

Cochrane Database Syst Rev. 2012 Dec;2012(12):CD004415.
28.3

Comparison 28 Masoprocol versus placebo, Outcome 3 Withdrawal due to adverse events.

Interventions for actinic keratoses

Cochrane Database Syst Rev. 2012 Dec;2012(12):CD004415.
15.4

Comparison 15 5% 5‐FU versus 10% masoprocol, Outcome 4 Withdrawal due to adverse events.

Interventions for actinic keratoses

Cochrane Database Syst Rev. 2012 Dec;2012(12):CD004415.
15.2

Comparison 15 5% 5‐FU versus 10% masoprocol, Outcome 2 Mean reduction of lesion counts.

Interventions for actinic keratoses

Cochrane Database Syst Rev. 2012 Dec;2012(12):CD004415.