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Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Haidar A. Shamran, Subah J. Hamza, Nahi Y. Yaseen, Ahmad A. Al-Juboory, Dennis D Taub, Robert L. Price, Mitzi Nagarkatti, Prakash S. Nagarkatti, Udai P. Singh

Int J Med Sci. 2014; 11(11): 1147–1153. Published online 2014 Aug 22. doi: 10.7150/ijms.9412

PMCID:: PMC4147641

Abstract Article PDF–643K

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Associations of common IL-4 gene polymorphisms with cancer risk: A meta-analysis

Yingxian Jia, Xiaochuan Xie, Xiaohan Shi, Shangwei Li

Mol Med Rep. 2017 Aug; 16(2): 1927–1945. Published online 2017 Jun 20. doi: 10.3892/mmr.2017.6822

PMCID:: PMC5561993

Abstract Article PDF–1.9M

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Interleukin 4 Affects Epilepsy by Regulating Glial Cells: Potential and Possible Mechanism

Lu Chen, Lin Zhu, Di Lu, Zhe Wu, Yanbing Han, Puying Xu, Lvhua Chang, Qian Wu

Front Mol Neurosci. 2020; 13: 554547. Published online 2020 Sep 4. doi: 10.3389/fnmol.2020.554547

PMCID:: PMC7500526

Abstract Article PDF–1.7M

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Genetic Association between Interleukin-4 Receptor Polymorphisms and Cancer Susceptibility: A Meta-Analysis Based on 53 Case-Control Studies

Yong Qi, Taofei Zeng, Song Fan, Li Zhang, Chaozhao Liang

J Cancer. 2019; 10(6): 1538–1549. Published online 2019 Feb 26. doi: 10.7150/jca.28137

PMCID:: PMC6485229

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Risk allelic load in Th2 and Th3 cytokines genes as biomarker of susceptibility to HPV-16 positive cervical cancer: a case control study

K. Torres-Poveda, A. I. Burguete-García, M. Bahena-Román, R. Méndez-Martínez, M. A. Zurita-Díaz, G. López-Estrada, K. Delgado-Romero, O. Peralta-Zaragoza, V. H. Bermúdez-Morales, D. Cantú, A. García-Carrancá, V. Madrid-Marina

BMC Cancer. 2016; 16: 330. Published online 2016 May 24. doi: 10.1186/s12885-016-2364-4

PMCID:: PMC4879749

Abstract Article PDF–855K

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Relationship between circulating inflammatory factors and glioma risk and prognosis: A meta‐analysis

Yuan Feng, Jia Wang, Dezhong Tan, Peng Cheng, Anhua Wu

Cancer Med. 2019 Dec; 8(17): 7454–7468. Published online 2019 Oct 9. doi: 10.1002/cam4.2585

PMCID:: PMC6885890

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The role of proinflammatory cytokines and CXC chemokines (CXCL1–CXCL16) in the progression of prostate cancer: insights on their therapeutic management

Amin Ullah, Wang Jiao, Bairong Shen

Cell Mol Biol Lett. 2024; 29: 73. Published online 2024 May 14. doi: 10.1186/s11658-024-00591-9

PMCID:: PMC11094955

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Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme

Aner Mesic, Marija Rogar, Petra Hudler, Nurija Bilalovic, Izet Eminovic, Radovan Komel

Sci Rep. 2021; 11: 17444. Published online 2021 Aug 31. doi: 10.1038/s41598-021-96935-y

PMCID:: PMC8408269

Abstract Article PDF–1.4M

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Integration of Biomarkers Into a Signature Profile of Persistent Traumatic Brain Injury Involving Autoimmune Processes Following Water Hammer Injury From Repetitive Head Impacts

Steven Kornguth, Neal Rutledge

Biomark Insights. 2018; 13: 1177271918808216. Published online 2018 Oct 29. doi: 10.1177/1177271918808216

PMCID:: PMC6207974

Abstract Article PDF–495K

Select item 824813710.

PubMed-indexed neurosurgical research productivity of Iraq-based neurosurgeons

Samer S. Hoz, Zahraa F. Al-Sharshahi, Ignatius N. Esene, Ali A. Dolachee, Ali M. Neamah, Aktham O. Al-Khafaji, Mohammed A. Al-Dhahir, Hatem Sadik

Surg Neurol Int. 2021; 12: 223. Published online 2021 May 17. doi: 10.25259/SNI_47_2021

PMCID:: PMC8248137

Abstract Article PDF–399K

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PMC Images search for Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Figure 1

Gel electrophoresis for (A) IL-4 PCR product visualized under UV light. M, 1000 bp marker, lane 1-10: from blood of glioma patients, lane 11-14: from blood of control group. The size of product is 280 bp and (B) IL-4R PCR product visualized under UV light. M, 1000 bp marker, lane 1-9: from blood of glioma patients, lane 10-11: from blood of control group. The size of product is 140 bp.

Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Int J Med Sci. 2014;11(11):1147-1153.
Figure 4

Mean serum concentration of IL-4 (pg/ml) in glioma patients and control group subjects as described in the materials and methods.

Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Int J Med Sci. 2014;11(11):1147-1153.
Figure 2

DNA sequencing from portions of the IL-4 gene from the forward strand are shown. The arrow indicates the position of SNP rs2070784 a: represents the genotype CC; b: TC and c: TT.

Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Int J Med Sci. 2014;11(11):1147-1153.
Figure 3

DNA sequencing for a portion of the IL-4R gene from the reverse strand is shown. The arrow indicates the position of SNP rs1805015 a: represents the genotype TT; b: TC and c: CC.

Impact of Single Nucleotide Polymorphism in IL-4, IL-4R Genes and Systemic Concentration of IL-4 on the Incidence of Glioma in Iraqi Patients

Int J Med Sci. 2014;11(11):1147-1153.

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