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Transactivation of human CAR1 transfected in human primary hepatocytes assessed as nuclear translocation at 30 uM by confocal laser scanning microscopy
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Transactivation of human CAR1 Ala retention mutant transfected in human HepG2 cells assessed as CYP2B6 expression at 1 to 30 uM after 24 hrs by luciferase reporter gene assay
Assay data:3 Tested
SummaryPubMed Citation
Transactivation of mouse CAR1 transfected in human HepG2 cells assessed as CYP2B6 expression at 1 to 30 uM after 24 hrs by luciferase reporter gene assay
Transactivation of human AhR at 0.1 to 30 uM after 24 to 48 hrs by cell-based luciferase reporter gene assay
Transactivation of rat PXR at 0.1 to 30 uM after 24 to 48 hrs by cell-based luciferase reporter gene assay
Transactivation of human PXR transfected in human HepG2 cells assessed as CYP2B6 expression at 1 to 30 uM by luciferase reporter gene assay
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