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Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells.
Assay data:6247 Active, 4 Activity ≤ 1 nM, 12419 Activity ≤ 1 µM, 344074 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells.
Assay data:9908 Active, 6263 Activity ≤ 1 µM, 345034 Tested
Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin
Assay data:87 Active, 17 Activity ≤ 1 nM, 79 Activity ≤ 1 µM, 90 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of type-3 17 beta-hydroxysteroid dehydrogenase expressed in HEK293 cells at 37 degree C pH7.4
Assay data:18 Active, 18 Activity ≤ 1 µM, 18 Tested
The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 3
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 1
Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cells
Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested
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