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Inhibition of pentagastrin-stimulated gastric acid secretion in the anesthetized rat after iv administration
Assay data:39 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of pentagastrin stimulated gastric acid secretion in anesthetized rat upon intravenous administration
Assay data:8 Tested
Compound was tested in vivo for gastric antisecretory activity after 5 hr of pylorus ligation of SD rat
Assay data:10 Tested
SummaryPubMed Citation
Compound was tested in vitro for H+/K+ ATPase activity in rabbit stomach preparations
Assay data:6 Active, 17 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of K+ -stimulated gastric ATPase activity was measured using lyophilized gastric vesicles at pH 7
Assay data:102 Active, 34 Activity ≤ 1 µM, 110 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mean percent peak inhibition of histamine-stimulated gastric acid secretion in the heidenhain pouch dog following a single dose of 4 umol/kg through oral administration.
Assay data:32 Tested
Mean percent peak inhibition of histamine-stimulated gastric acid secretion in the heidenhain pouch dog following a single dose of 1 umol/kg through iv administration.
Assay data:43 Tested
Histamine-stimulated gastric acid secretion in Heidenhain pouch dog at 4uM/Kg, on iv administration of the compound
Assay data:2 Tested
Histamine-stimulated gastric acid secretion in Heidenhain pouch dog at 1uM/Kg, on iv administration of the compound
Inhibition of histamine stimulated gastric acid secretion was tested in heidenhain pouch dog upon oral administration
Inhibition of histamine stimulated gastric acid secretion was tested in heidenhain pouch dog upon intravenous administration
Assay data:3 Tested
Concentration required to inhibit the activity of K+ stimulated gastric ATPase
Assay data:20 Active, 4 Activity ≤ 1 µM, 33 Tested
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