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| Status |
Public on May 14, 2010 |
| Title |
Transcriptional analysis of an E2F gene signature as a biomarker of activity of the cyclin-dependent kinase inhibitor PHA-793887 in tumor and skin biopsies from a phase I clinical study |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Microarray analysis of transcriptional changes in biopsies of solid tumors from patients treated in a Phase I study with the Cdk inhibitor PHA-793887.
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| Overall design |
7 patient biopsies pre- and post-treatment in dye swap. Tumors are of different origins, and are described in the accompanying manuscript.
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| Contributor(s) |
Locatelli G, Bosotti R, Ciomei M, Brasca MG, Calogero R, Mercurio C, Fiorentini F, Bertolotti M, Scacheri E, Scaburri A, Galvani A, Pesenti E, De Baere T, Soria J, Lazar V, Isacchi A |
| Citation(s) |
20423997 |
| Submission date |
Oct 14, 2009 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Roberta Bosotti |
| E-mail(s) |
roberta.bosotti@nervianoms.com
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| Organization name |
Nerviano Medical Sciences srl
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| Department |
Biotechnology
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| Lab |
Genomics
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| Street address |
viale Pasteur,10
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| City |
Nerviano |
| State/province |
MI |
| ZIP/Postal code |
20014 |
| Country |
Italy |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA121365 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE18553_RAW.tar |
182.7 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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