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    lsrD Autoinducer-2 ABC transporter membrane subunit LsrD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946264, updated on 4-Feb-2024

    Summary

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    Gene symbol
    lsrD
    Gene description
    Autoinducer-2 ABC transporter membrane subunit LsrD
    Primary source
    ASAP:ABE-0005061
    Locus tag
    b1515
    See related
    ECOCYC:G6802
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1508; ydeZ
    Summary
    LsrD is paralogous to ribose transport membrane channel protein RbsC and is in an operon regulated by LsrR and LuxS, through AI-2. [More information is available at EcoGene: EG13808]. LsrD is a membrane component of a predicted ATP-dependent sugar transporter. [More information is available at EcoCyc: G6802].
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    Genomic context

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    Sequence:
    NC_000913.3 (1604047..1605039)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor LsrR Neighboring gene Autoinducer-2 ABC transporter ATP binding subunit Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrC Neighboring gene Autoinducer-2 ABC transporter periplasmic binding protein Neighboring gene 3-hydroxy-2,4-pentadione 5-phosphate thiolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Taga ME, et al. Mol Microbiol, 2001 Nov. PMID 11722742
    2. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. Xavier KB, et al. J Bacteriol, 2005 Jan. PMID 15601708, Free PMC Article
    3. Cyclic AMP (cAMP) and cAMP receptor protein influence both synthesis and uptake of extracellular autoinducer 2 in Escherichia coli. Wang L, et al. J Bacteriol, 2005 Mar. PMID 15743955, Free PMC Article
    4. Cell-to-cell signalling in Escherichia coli and Salmonella enterica. Ahmer BM. Mol Microbiol, 2004 May. PMID 15130116
    5. luxS-dependent gene regulation in Escherichia coli K-12 revealed by genomic expression profiling. Wang L, et al. J Bacteriol, 2005 Dec. PMID 16321939, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in autoinducer AI-2 transmembrane transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in quorum sensing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Autoinducer-2 ABC transporter membrane subunit LsrD
    NP_416032.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1604047..1605039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416032.1 Autoinducer-2 ABC transporter membrane subunit LsrD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416032.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A827XXT6, A0A8T5YDF9, A0A8T6A379, F4V222
      Conserved Domains (1) summary
      PRK15038
      Location:1 → 330
      PRK15038; autoinducer 2 ABC transporter permease LsrD
    Nucleotide Protein
    Heading Accession and Version

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