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    Ten-a Tenascin accessory [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32183, updated on 27-Mar-2024

    Summary

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    Official Symbol
    Ten-aprovided by FlyBase
    Official Full Name
    Tenascin accessoryprovided by FlyBase
    Primary source
    FLYBASE:FBgn0267001
    Locus tag
    Dmel_CG42338
    See related
    AllianceGenome:FB:FBgn0267001
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    1.2; cbd; CG11270; CG12720; CG15733; CG18182; CG2578; CG2590; CG32659; CG42338; Dmel\CG42338; Dmtena; DmtenA; ten-a; Ten11A; tenA; tenA(AT)[[14]]; ten[a]; Ten[a]
    Old locus tag
    Dmel_CG12720; Dmel_CG15733; Dmel_CG32659
    Summary
    Enables protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including nervous system development; regulation of cell-cell adhesion; and synapse organization. Located in several cellular components, including cytoskeleton of presynaptic active zone; neuromuscular junction; and presynaptic membrane. Is expressed in several structures, including embryonic abdominal segment 9; embryonic/larval nervous system; olfactory system; presumptive embryonic/larval system; and spermatozoon. Orthologous to human TENM2 (teneurin transmembrane protein 2) and TENM3 (teneurin transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    11A2-11A8; 1-38 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12043698..12335214)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11937731..12229247)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43960 Neighboring gene Cytochrome P450 311a1 Neighboring gene Cytochrome P450 318a1 Neighboring gene long non-coding RNA:CR43961 Neighboring gene long non-coding RNA:CR32657 Neighboring gene Uch-L5-related Neighboring gene long non-coding RNA:CR32658 Neighboring gene Mucin 11A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene moonshiner Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 11a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Behavioral idiosyncrasy reveals genetic control of phenotypic variability. Ayroles JF, et al. Proc Natl Acad Sci U S A, 2015 May 26. PMID 25953335, Free PMC Article
    2. Expression of Drosophila Ten-a, a dimeric receptor during embryonic development. Fascetti N, et al. Mech Dev, 2002 Jun. PMID 12175511
    3. The Tenets of Teneurin: Conserved Mechanisms Regulate Diverse Developmental Processes in the Drosophila Nervous System. DePew AT, et al. Front Neurosci, 2019. PMID 30760977, Free PMC Article
    4. Fine-mapping natural alleles: quantitative complementation to the rescue. Turner TL. Mol Ecol, 2014 May. PMID 24628660, Free PMC Article
    5. Tena, a Drosophila gene related to tenascin, shows selective transcript localization. Baumgartner S, et al. Mech Dev, 1993 Mar. PMID 7684246

    See all (100) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ten-a acts in olfactory receptor neurons to organize presynaptic active zones via the spectrin cytoskeleton.
      Title: Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins.
    2. Our result revealed the function of ten-a in central brain development, and possible cellular mechanism underlying Drosophila fan-shaped body formation.
      Title: Ten-a affects the fusion of central complex primordia in Drosophila.
    3. identification of two evolutionarily conserved, epidermal growth factor (EGF)-repeat containing transmembrane Teneurin proteins, Ten-m and Ten-a, as synaptic-partner-matching molecules between projection neuron dendrites and olfactory receptor neuron axons
      Title: Teneurins instruct synaptic partner matching in an olfactory map.
    4. study identifies the Teneurins as a key bi-directional trans-synaptic signal involved in general synapse organization, and demonstrates that proteins such as these can also regulate target selection
      Title: Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice.
    5. The Ten-a protein, a dimeric receptor of about 500 kDa is mainly expressed on axons of the embryonic central nervous system and on muscle attachment sites
      Title: Expression of Drosophila Ten-a, a dimeric receptor during embryonic development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: 12163544-12163806 mobile_element_type = transposon:INE-1{}1864
    • Loc: 12168193-12173562 mobile_element_type = transposon:I{}112

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein heterodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in central complex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of alignment of postsynaptic density and presynaptic active zone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in maintenance of alignment of postsynaptic density and presynaptic active zone IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maintenance of presynaptic active zone structure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuromuscular synaptic transmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of heterotypic cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in postsynaptic membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in presynaptic membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of homotypic cell-cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of terminal button organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synapse organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synaptic assembly at neuromuscular junction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic target attraction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic target recognition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in synaptic target recognition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic vesicle membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton of presynaptic active zone IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in extracellular matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in presynaptic active zone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in presynaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tenascin accessory
    Names
    CG42338-PD
    CG42338-PE
    CG42338-PF
    CG42338-PG
    CG42338-PI
    CG42338-PK
    CG42338-PL
    CG42338-PM
    CG42338-PN
    CG42338-PO
    CG42338-PP
    Ten-a-PD
    Ten-a-PE
    Ten-a-PF
    Ten-a-PG
    Ten-a-PI
    Ten-a-PK
    Ten-a-PL
    Ten-a-PM
    Ten-a-PN
    Ten-a-PO
    Ten-a-PP
    Teneurin-a
    central body defect
    central-body-defect
    tenascin-like molecule accessory
    teneurin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12043698..12335214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169259.3 → NP_001162730.2  tenascin accessory, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162730.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z145, E1JJM3
      Conserved Domains (9) summary
      COG3209
      Location:2388 → 2949
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:1162 → 1192
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1666 → 1712
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2930 → 3006
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:998 → 1162
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:2204 → 2241
      RHS_repeat; RHS Repeat
      pfam07974
      Location:1032 → 1057
      EGF_2; EGF-like domain
      pfam15636
      Location:3265 → 3340
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1613 → 1918
      NHL; NHL repeat unit of beta-propeller proteins

    2. NM_001169261.3 → NP_001162732.2  tenascin accessory, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162732.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VYN8
      Conserved Domains (9) summary
      COG3209
      Location:2397 → 2958
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:1163 → 1192
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1675 → 1721
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2939 → 3015
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:998 → 1162
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:2213 → 2250
      RHS_repeat; RHS Repeat
      pfam07974
      Location:1032 → 1057
      EGF_2; EGF-like domain
      pfam15636
      Location:3274 → 3349
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1622 → 1927
      NHL; NHL repeat unit of beta-propeller proteins

    3. NM_001169260.3 → NP_001162731.1  tenascin accessory, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162731.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24550, Q9VYN8
      UniProtKB/TrEMBL
      M9PJK5
      Conserved Domains (9) summary
      COG3209
      Location:2014 → 2575
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1292 → 1338
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2556 → 2632
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1830 → 1867
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2891 → 2966
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1239 → 1544
      NHL; NHL repeat unit of beta-propeller proteins

    4. NM_001144718.3 → NP_001138190.1  tenascin accessory, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138190.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24550, Q9VYN8
      UniProtKB/TrEMBL
      M9PJK5
      Conserved Domains (9) summary
      COG3209
      Location:2014 → 2575
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1292 → 1338
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2556 → 2632
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1830 → 1867
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2891 → 2966
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1239 → 1544
      NHL; NHL repeat unit of beta-propeller proteins

    5. NM_001144717.4 → NP_001138189.1  tenascin accessory, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138189.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z145, E1JJM3
      Conserved Domains (9) summary
      COG3209
      Location:2388 → 2949
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:1162 → 1192
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1666 → 1712
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2930 → 3006
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:998 → 1162
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:2204 → 2241
      RHS_repeat; RHS Repeat
      pfam07974
      Location:1032 → 1057
      EGF_2; EGF-like domain
      pfam15636
      Location:3265 → 3340
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1613 → 1918
      NHL; NHL repeat unit of beta-propeller proteins

    6. NM_001272554.2 → NP_001259483.1  tenascin accessory, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259483.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24550, Q9VYN8
      UniProtKB/TrEMBL
      M9PJK5
      Conserved Domains (9) summary
      COG3209
      Location:2014 → 2575
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1292 → 1338
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2556 → 2632
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1830 → 1867
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2891 → 2966
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1239 → 1544
      NHL; NHL repeat unit of beta-propeller proteins

    7. NM_001258713.2 → NP_001245642.1  tenascin accessory, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245642.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NF26
      Conserved Domains (9) summary
      COG3209
      Location:2023 → 2584
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1301 → 1347
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2565 → 2641
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1839 → 1876
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2900 → 2975
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1248 → 1553
      NHL; NHL repeat unit of beta-propeller proteins

    8. NM_001258712.2 → NP_001245641.1  tenascin accessory, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245641.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NF26
      Conserved Domains (9) summary
      COG3209
      Location:2023 → 2584
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1301 → 1347
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2565 → 2641
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1839 → 1876
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2900 → 2975
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1248 → 1553
      NHL; NHL repeat unit of beta-propeller proteins

    9. NM_001258711.2 → NP_001245640.1  tenascin accessory, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245640.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24550, Q9VYN8
      UniProtKB/TrEMBL
      M9PJK5
      Conserved Domains (9) summary
      COG3209
      Location:2014 → 2575
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1292 → 1338
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2556 → 2632
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1830 → 1867
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2891 → 2966
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1239 → 1544
      NHL; NHL repeat unit of beta-propeller proteins

    10. NM_001169258.2 → NP_001162729.1  tenascin accessory, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162729.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJM6
      Conserved Domains (9) summary
      COG3209
      Location:1912 → 2473
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:687 → 716
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1190 → 1236
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2454 → 2530
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:522 → 686
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1728 → 1765
      RHS_repeat; RHS Repeat
      pfam07974
      Location:556 → 581
      EGF_2; EGF-like domain
      pfam15636
      Location:2789 → 2864
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1137 → 1442
      NHL; NHL repeat unit of beta-propeller proteins

    11. NM_078582.4 → NP_511137.3  tenascin accessory, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_511137.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24550, Q9VYN8
      UniProtKB/TrEMBL
      M9PJK5
      Related
      FBpp0289136
      Conserved Domains (9) summary
      COG3209
      Location:2014 → 2575
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:789 → 818
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:1292 → 1338
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2556 → 2632
      Rhs_assc_core; RHS repeat-associated core domain
      pfam01500
      Location:624 → 788
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam05593
      Location:1830 → 1867
      RHS_repeat; RHS Repeat
      pfam07974
      Location:658 → 683
      EGF_2; EGF-like domain
      pfam15636
      Location:2891 → 2966
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      cl18310
      Location:1239 → 1544
      NHL; NHL repeat unit of beta-propeller proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z145 B7Z145
    E1JJM6 E1JJM6
    I6LEU4 I6LEU4
    I6LEU5 I6LEU5
    I6LEU6 I6LEU6
    I6LEU7 I6LEU7
    I6LEU8 I6LEU8
    M9NF26 M9NF26
    M9PJK5 M9PJK5
    Q8MQJ6 Q8MQJ6
    Q9VYN8.2 Q9VYN8

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