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    cids-2 CID domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172691, updated on 25-Apr-2024

    Summary

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    Gene symbol
    cids-2
    Gene description
    CID domain-containing protein
    Primary source
    WormBase:WBGene00009451
    Locus tag
    CELE_F36A2.1
    See related
    AllianceGenome:WB:WBGene00009451
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Predicted to be part of RNA polymerase II, holoenzyme. Orthologous to human RPRD2 (regulation of nuclear pre-mRNA domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (8804799..8808081, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Disintegrin and metalloproteinase domain-containing protein 10 homolog Neighboring gene Malate dehydrogenase Neighboring gene DUS-like FMN-binding domain-containing protein Neighboring gene 14 kDa phosphohistidine phosphatase-like Neighboring gene Fibronectin type-III domain-containing protein Neighboring gene Cytochrome c oxidase subunit 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rhn1, a nuclear protein, is required for suppression of meiotic mRNAs in mitotically dividing fission yeast. Sugiyama T, et al. PLoS One, 2012. PMID 22912768, Free PMC Article
    2. Nuclear pre-mRNA 3'-end processing regulates synapse and axon development in C. elegans. Van Epps H, et al. Development, 2010 Jul. PMID 20530551, Free PMC Article
    3. Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen. Cui M, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18946043, Free PMC Article
    4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA 3'-end processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CID domain-containing protein
    NP_001122471.1
    • Confirmed by transcript evidence
    NP_001122472.1
    • Confirmed by transcript evidence
    NP_492380.2
    • Confirmed by transcript evidence
    NP_871883.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8804799..8808081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059979.6 → NP_492380.2  CID domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492380.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVN9
      Conserved Domains (2) summary
      smart00582
      Location:5 → 133
      RPR; domain present in proteins, which are involved in regulation of nuclear pre-mRNA
      PHA03247
      Location:369 → 553
      PHA03247; large tegument protein UL36; Provisional

    2. NM_001128999.4 → NP_001122471.1  CID domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122471.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2V0
      Conserved Domains (2) summary
      smart00582
      Location:5 → 132
      RPR; domain present in proteins, which are involved in regulation of nuclear pre-mRNA
      PHA03247
      Location:373 → 557
      PHA03247; large tegument protein UL36; Provisional

    3. NM_001129000.5 → NP_001122472.1  CID domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122472.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2V1
      Conserved Domains (2) summary
      smart00582
      Location:20 → 134
      RPR; domain present in proteins, which are involved in regulation of nuclear pre-mRNA
      PHA03247
      Location:375 → 559
      PHA03247; large tegument protein UL36; Provisional

    4. NM_182083.7 → NP_871883.2  CID domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871883.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I4J5
      Conserved Domains (2) summary
      smart00582
      Location:5 → 132
      RPR; domain present in proteins, which are involved in regulation of nuclear pre-mRNA
      PHA03247
      Location:367 → 551
      PHA03247; large tegument protein UL36; Provisional

    RNA

    1. NR_023944.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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