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    rpl-7 Large ribosomal subunit protein uL30 [ Caenorhabditis elegans ]

    Gene ID: 171602, updated on 5-May-2024

    Summary

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    Gene symbol
    rpl-7
    Gene description
    Large ribosomal subunit protein uL30
    Primary source
    WormBase:WBGene00004418
    Locus tag
    CELE_F53G12.10
    See related
    AllianceGenome:WB:WBGene00004418
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to several human genes including RPL7 (ribosomal protein L7). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (111038..112272)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ras-related protein rab-11.1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GST_C_6 domain-containing protein;Metaxin glutathione S-transferase domain-containing protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. mRNA surveillance of expressed pseudogenes in C. elegans. Mitrovich QM, et al. Curr Biol, 2005 May 24. PMID 15916954
    2. Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans. Mitrovich QM, et al. Genes Dev, 2000 Sep 1. PMID 10970881, Free PMC Article
    3. A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress. Li H, et al. Proteome Sci, 2010 Sep 21. PMID 20858264, Free PMC Article
    4. Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons. Johns L, et al. Mol Cell Biol, 2007 Aug. PMID 17562857, Free PMC Article
    5. An improved method for proteomics studies in C. elegans by fluorogenic derivatization, HPLC isolation, enzymatic digestion and liquid chromatography--tandem mass spectrometric identification. Masuda M, et al. Biomed Chromatogr, 2005 Sep. PMID 15654727

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Large ribosomal subunit protein uL30
    NP_490676.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      111038..112272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058275.7 → NP_490676.1  Large ribosomal subunit protein uL30 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490676.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01802
      Conserved Domains (3) summary
      cd01657
      Location:85 → 244
      Ribosomal_L7_archeal_euk; Ribosomal protein L7, which is found in archaea and eukaryotes but not in prokaryotes, binds domain II of the 23S rRNA as well as the 5S rRNA and is one of five ribosomal proteins that mediate the interactions 5S rRNA makes with the ribosome. The ...
      TIGR01310
      Location:12 → 244
      uL30_euk; 60S ribosomal protein uL30, eukaryotic form
      pfam08079
      Location:13 → 83
      Ribosomal_L30_N; Ribosomal L30 N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O01802.1

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