| Long non-coding RNA DUXAP10 exerts oncogenic properties in osteosarcoma by recruiting HuR to enhance SOX18 mRNA stability. | Long non-coding RNA DUXAP10 exerts oncogenic properties in osteosarcoma by recruiting HuR to enhance SOX18 mRNA stability.
Wang G, Zhang Q, Wang Q, Wang J, Chen L, Sun Q, Miao D., Free PMC Article | 10/8/2022 |
| Oncogenic pseudogene DUXAP10 knockdown suppresses proliferation and invasion and induces apoptosis of papillary thyroid carcinoma cells by inhibition of Akt/mTOR pathway. | Oncogenic pseudogene DUXAP10 knockdown suppresses proliferation and invasion and induces apoptosis of papillary thyroid carcinoma cells by inhibition of Akt/mTOR pathway.
Li J, Jiang L, Liu Z, Li Y, Xu Y, Liu H. | 10/16/2021 |
| Downregulation of long non-coding RNA DUXAP10 inhibits proliferation, migration, and invasion of renal cell carcinoma. | Downregulation of long non-coding RNA DUXAP10 inhibits proliferation, migration, and invasion of renal cell carcinoma.
Chen J, Wang XF, Qin YC, Gong YB, Wang L, Li NC. | 06/26/2021 |
| Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability. | Long noncoding RNA DUXAP10 promotes the stemness of glioma cells by recruiting HuR to enhance Sox12 mRNA stability.
Wu B, Yang C, Fang Y, Ding W, Zhang Y. | 05/8/2021 |
| microRNA-1914, which is regulated by lncRNA DUXAP10, inhibits cell proliferation by targeting the GPR39-mediated PI3K/AKT/mTOR pathway in HCC. | microRNA-1914, which is regulated by lncRNA DUXAP10, inhibits cell proliferation by targeting the GPR39-mediated PI3K/AKT/mTOR pathway in HCC.
Sun L, Wang L, Chen T, Yao B, Wang Y, Li Q, Yang W, Liu Z., Free PMC Article | 09/26/2020 |
| DUXAP10 plays a critical role in regulating HCC development, potentially by regulating EMT and cell proliferation through the PI3K/Akt and Wnt/beta-catenin signaling. Inhibition of DUXAP10 in HCC HepG2 cells could attenuate the EMT and cell proliferation and invasion. Therefore, DUXAP10 might be a promising therapy target to inhibit the growth of HCC. | DUXAP10 inhibition attenuates the proliferation and metastasis of hepatocellular carcinoma cells by regulation of the Wnt/β-catenin and PI3K/Akt signaling pathways.
Han K, Li C, Zhang X, Shang L., Free PMC Article | 07/4/2020 |
| Knockdown of DUXAP10 in K652 and KG-1 cells can remarkably inhibit cell proliferation, promote cycle arrest and apoptosis. Western blot and flow cytometry results demonstrated that DUXAP10 can reduce apoptosis by inhibiting PTEN expression. | DUXAP10 regulates proliferation and apoptosis of chronic myeloid leukemia via PTEN pathway.
Yao R, Feng WT, Xu LJ, Zhong XM, Liu H, Sun Y, Zhou LL. | 11/9/2019 |
| our findings illuminate how increased DUXAP10 confers an oncogenic function in GC development and progression that may serve as a candidate prognostic biomarker and target for clinical management of GC. | Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and β-catenin in gastric cancer.
Xu Y, Yu X, Wei C, Nie F, Huang M, Sun M., Free PMC Article | 05/11/2019 |
| DUXAP10 is upregulated in CRC tissues and its overexpression may be associated with the poor prognosis of CRC patients. | The pseudogene derived from long non-coding RNA DUXAP10 promotes colorectal cancer cell growth through epigenetically silencing of p21 and PTEN.
Lian Y, Xu Y, Xiao C, Xia R, Gong H, Yang P, Chen T, Wu D, Cai Z, Zhang J, Wang K., Free PMC Article | 02/23/2019 |
| Results suggested that the expression level of DUXAP10 was significantly enhanced in cancer cells. After knockdown of DUXAP10, cell proliferation was inhibited, cell cycle was arrested at G0/G1 phase, and apoptosis was increased in T24 and 5637 cells. | Knockdown of DUXAP10 inhibits proliferation and promotes apoptosis in bladder cancer cells via PI3K/Akt/mTOR signaling pathway.
Lv XY, Ma L, Chen JF, Yu R, Li Y, Yan ZJ, Cheng Y, Ma Q. | 06/9/2018 |