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    KLHL22 kelch like family member 22 [ Gallus gallus (chicken) ]

    Gene ID: 416940, updated on 5-Mar-2024

    Summary

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    Symbol
    KLHL22provided by CGNC
    Full Name
    kelch like family member 22provided by CGNC
    Primary source
    CGNC:4838
    See related
    Ensembl:ENSGALG00010026237
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (8287066..8302003, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (8297729..8312679, complement)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene calcineurin binding protein 1 Neighboring gene MGA, MAX dimerization protein Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene mediator complex subunit 15 Neighboring gene sphingomyelin phosphodiesterase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein monoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitotic spindle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in polar microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like protein 22
    Names
    kelch-like 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      8287066..8302003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046901332.1 → XP_046757288.1  kelch-like protein 22

      UniProtKB/TrEMBL
      E1BS99

    2. XM_046901330.1 → XP_046757286.1  kelch-like protein 22

      UniProtKB/TrEMBL
      E1BS99
      Related
      ENSGALP00010039359.1, ENSGALT00010063849.1

    3. XM_415234.8 → XP_415234.1  kelch-like protein 22

      See identical proteins and their annotated locations for XP_415234.1

      UniProtKB/TrEMBL
      E1BS99
      Conserved Domains (3) summary
      PHA03098
      Location:52 → 574
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:340 → 385
      Kelch; KELCH repeat [structural motif]
      cd18251
      Location:27 → 151
      BTB_POZ_KLHL22; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 22 (KLHL22)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      8297729..8312679 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928413.1 → XP_046784369.1  kelch-like protein 22

      UniProtKB/TrEMBL
      E1BS99

    2. XM_046928412.1 → XP_046784368.1  kelch-like protein 22

      UniProtKB/TrEMBL
      E1BS99

    3. XM_040684864.2 → XP_040540798.1  kelch-like protein 22

      UniProtKB/TrEMBL
      E1BS99
      Conserved Domains (3) summary
      PHA03098
      Location:52 → 574
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:340 → 385
      Kelch; KELCH repeat [structural motif]
      cd18251
      Location:27 → 151
      BTB_POZ_KLHL22; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 22 (KLHL22)
    Nucleotide Protein
    Heading Accession and Version

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