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    Thsd7b thrombospondin type 1 domain containing 7B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289007, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Thsd7bprovided by RGD
    Official Full Name
    thrombospondin type 1 domain containing 7Bprovided by RGD
    Primary source
    RGD:1306938
    See related
    EnsemblRapid:ENSRNOG00000003878 AllianceGenome:RGD:1306938
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306938
    Summary
    Predicted to be involved in actin cytoskeleton reorganization. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human THSD7B (thrombospondin type 1 domain containing 7B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 23.5), Adrenal (RPKM 11.6) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    13q13
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (43320895..44219546)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (40768567..41667262)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (46026943..46931619)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 26 Neighboring gene GABA type A receptor associated protein like 2, pseudogene 1 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC120096244 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134481489 Neighboring gene mitochondrial ribosomal protein L30, pseudogene 2 Neighboring gene CD55 molecule (Cromer blood group)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    thrombospondin type-1 domain-containing protein 7B
    Names
    thrombospondin, type I, domain containing 7B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191669.1 → NP_001178598.1  thrombospondin type-1 domain-containing protein 7B precursor

      See identical proteins and their annotated locations for NP_001178598.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/TrEMBL
      A0A8I5ZSV0, F1LPD7
      Related
      ENSRNOP00000081745.2, ENSRNOT00000115425.2
      Conserved Domains (2) summary
      pfam19028
      Location:337 → 398
      TSP1_spondin; Spondin-like TSP1 domain
      pfam19030
      Location:1063 → 1123
      TSP1_ADAMTS; Thrombospondin type 1 domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      43320895..44219546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090425.1 → XP_038946353.1  thrombospondin type-1 domain-containing protein 7B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZSV0, F1LPD7
      Conserved Domains (2) summary
      pfam19028
      Location:337 → 398
      TSP1_spondin; Spondin-like TSP1 domain
      pfam19030
      Location:1063 → 1123
      TSP1_ADAMTS; Thrombospondin type 1 domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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