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    MIR99B microRNA mir-99b [ Canis lupus familiaris (dog) ]

    Gene ID: 100886182, updated on 22-Jan-2024

    Summary

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    Gene symbol
    MIR99B
    Gene description
    microRNA mir-99b
    See related
    Ensembl:ENSCAFG00845004861 miRBase:MI0008003
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    cfa-mir-99b
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

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    See MIR99B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (105910842..105910901, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (104974438..104974497, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (106018965..106019024, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (105583074..105583133, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (105224190..105224249, complement)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene sperm acrosome associated 6 Neighboring gene uncharacterized LOC111099011 Neighboring gene microRNA let-7e Neighboring gene microRNA mir-125a Neighboring gene sialic acid-binding Ig-like lectin 14 Neighboring gene sialic acid-binding Ig-like lectin 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Discovering microRNAs from deep sequencing data using miRDeep. Friedländer MR, et al. Nat Biotechnol, 2008 Apr. PMID 18392026
    2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • microRNA 99b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_049234.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      JAAUVH010000354
      Related
      ENSCAFT00845008693.1

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      105910842..105910901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      105583074..105583133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      105224190..105224249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      106018965..106019024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      104974438..104974497 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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