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    AvBD14 avian beta-defensin 14 [ Gallus gallus (chicken) ]

    Gene ID: 100858701, updated on 3-Apr-2024

    Summary

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    Symbol
    AvBD14provided by CGNC
    Full Name
    avian beta-defensin 14provided by CGNC
    Primary source
    CGNC:64397
    See related
    Ensembl:ENSGALG00010007881
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    DEFB1; GAL14; Gal-14
    Orthologs
    human all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (107276908..107279791, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (107039698..107042751, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene avian beta-defensin 5 Neighboring gene avian beta-defensin 4 Neighboring gene XK related 5 Neighboring gene translocation associated membrane protein 2 Neighboring gene EF-hand domain containing 1 Neighboring gene progestin and adipoQ receptor family member 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens. Zhang LY, et al. Br Poult Sci, 2020 Aug. PMID 32290685
    2. Avian host defense peptides. Cuperus T, et al. Dev Comp Immunol, 2013 Nov. PMID 23644014
    3. Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins. Derache C, et al. Antimicrob Agents Chemother, 2009 Nov. PMID 19738012, Free PMC Article
    4. Avian beta-defensin nomenclature: a community proposed update. Lynn DJ, et al. Immunol Lett, 2007 May 15. PMID 17467809
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens.
      Title: Association of three beta-defensin gene (AvBD4, AvBD5, AvBD14) polymorphisms with carrier-state susceptibility to salmonella in chickens.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CCR6 chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response in mucosa IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gallinacin-14
    Names
    Gallinacin-14
    beta-defensin 14
    defensin beta 1
    gallinacin 14
    gallinacin-14-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348511.2 → NP_001335440.1  gallinacin-14 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000070
      UniProtKB/Swiss-Prot
      Q0E4V3
      UniProtKB/TrEMBL
      A0A3Q2TTA1
      Related
      ENSGALP00010010302.1, ENSGALT00010018752.1
      Conserved Domains (1) summary
      pfam00711
      Location:27 → 61
      Defensin_beta; Beta defensin

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      107276908..107279791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040696683.2 → XP_040552617.1  gallinacin-14 isoform X1

    2. XM_025148463.3 → XP_025004231.1  gallinacin-14 isoform X2

      UniProtKB/Swiss-Prot
      Q0E4V3
      UniProtKB/TrEMBL
      A0A3Q2TTA1
      Conserved Domains (1) summary
      pfam00711
      Location:27 → 61
      Defensin_beta; Beta defensin

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      107039698..107042751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046912836.1 → XP_046768792.1  gallinacin-14 isoform X1

    2. XM_046912837.1 → XP_046768793.1  gallinacin-14 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2TTA1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E4V3.1 GenPept UniProtKB/Swiss-Prot:Q0E4V3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.