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    SPAC4F10.04 putative type 2A protein phosphatase regulator [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543619, updated on 11-Apr-2024

    Summary

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    Gene symbol
    SPAC4F10.04
    Gene description
    putative type 2A protein phosphatase regulator
    Primary source
    PomBase:SPAC4F10.04
    Locus tag
    SPAC4F10.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4836136..4837590)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene aspartyl aminopeptidase Aap1 Neighboring gene putative tRNA 2'-O-ribose methyltransferase Neighboring gene putative lipoate-protein ligase Neighboring gene miscRNA Neighboring gene putative BUD22 family ribosome small subunit biogenesis protein Neighboring gene autophagy-associated protein kinase regulatory subunit Atg13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Using genetic buffering relationships identified in fission yeast to reveal susceptibilities in cells lacking hamartin or tuberin function. Rayhan A, et al. Biol Open, 2018 Jan 17. PMID 29343513, Free PMC Article
    2. Characterization of ypa1 and ypa2, the Schizosaccharomyces pombe orthologs of the peptidyl proyl isomerases that activate PP2A, reveals a role for Ypa2p in the regulation of cytokinesis. Goyal A, et al. Genetics, 2012 Apr. PMID 22267499, Free PMC Article
    3. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Henry TC, et al. Eukaryot Cell, 2011 Feb. PMID 21169418, Free PMC Article
    4. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
    5. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signaling NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative type 2A protein phosphatase regulator

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4836136..4837590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020174.2 → NP_594747.1  putative type 2A protein phosphatase regulator [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594747.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O36016
      Conserved Domains (1) summary
      COG5057
      Location:18 → 325
      LAG1; Phosphotyrosyl phosphatase activator [Cell division and chromosome partitioning / Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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