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    UBP4 ubiquitin-specific protease 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816763, updated on 15-Oct-2023

    Summary

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    Gene symbol
    UBP4
    Gene description
    ubiquitin-specific protease 4
    Primary source
    Araport:AT2G22310
    Locus tag
    AT2G22310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATUBP4; T26C19.3; T26C19_3; ubiquitin-specific protease 4; UBIQUITIN-SPECIFIC PROTEASE 4
    Summary
    Encodes a ubiquitin-specific protease.
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    Genomic context

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    See UBP4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (9476578..9478959, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene RAB GTPase homolog H1D Neighboring gene signal responsive 1 Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ubiquitin-specific protease subfamily UBP3/UBP4 is essential for pollen development and transmission in Arabidopsis. Doelling JH, et al. Plant Physiol, 2007 Nov. PMID 17905865, Free PMC Article
    2. AtUBP3 and AtUBP4 are two closely related Arabidopsis thaliana ubiquitin-specific proteases present in the nucleus. Chandler JS, et al. Mol Gen Genet, 1997 Jul. PMID 9268021
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study reports on the characteristics of UBP3 and UBP4 in A. thaliana.
      Title: The ubiquitin-specific protease subfamily UBP3/UBP4 is essential for pollen development and transmission in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001335796.1
    NM_001335797.1
    NM_127796.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin-specific protease 4
    NP_001318266.1
    • ubiquitin-specific protease 4 (UBP4); CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 3 (TAIR:AT4G39910.1).
    NP_565532.1
    • ubiquitin-specific protease 4 (UBP4); CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 3 (TAIR:AT4G39910.1); Has 8879 Blast hits to 7429 proteins in 247 species: Archae - 0; Bacteria - 4; Metazoa - 4505; Fungi - 1682; Plants - 966; Viruses - 3; Other Eukaryotes - 1719 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9476578..9478959 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127796.3 → NP_565532.1  ubiquitin-specific protease 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565532.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O24455, Q8LAM0
      UniProtKB/TrEMBL
      A0A178W1M0, A0A5S9X050
      Conserved Domains (1) summary
      cd02663
      Location:24 → 360
      Peptidase_C19G; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    2. NM_001335797.1 → NP_001324040.1  ubiquitin-specific protease 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AYX2, A0A5S9X050

    3. NM_001335796.1 → NP_001318266.1  ubiquitin-specific protease 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9X050, F4IJH1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LAM0.2

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