CYCA2;4 Cyclin A2;4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: CYCA2;4
Gene description: Cyclin A2;4
Primary source: Araport:AT1G80370
Locus tag: AT1G80370
See related: TAIR:AT1G80370
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Cyclin A2;4; F5I6.12; F5I6_12
Summary: Encodes a A2-type cyclin. Contributes to the fine-tuning of local proliferation during plant development.
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Genomic context

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See CYCA2;4 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 11

Sequence:: Chromosome: 1; NC_003070.9 (30213705..30217102)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

We show that stage-specific expression of CYCA2;1 and CYCA2;4 in vein development depends on regulatory elements containing, respectively, one and three evolutionarily conserved transcription-factor binding sites
Title: Transcriptional control of early vein expression of CYCA2; 1 and CYCA2;4 in Arabidopsis leaves.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_106686.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell division	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mitotic cell cycle phase transition	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of G2/M transition of mitotic cell cycle	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within stomatal complex development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Cyclin A2;4

NP_178153.1

Cyclin A2;4 (CYCA2;4); CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin (InterPro:IPR006670), G2/mitotic-specific cyclin A (InterPro:IPR015453), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400); BEST Arabidopsis thaliana protein match is: CYCLIN A2;3 (TAIR:AT1G15570.1); Has 4103 Blast hits to 4099 proteins in 369 species: Archae - 0; Bacteria - 2; Metazoa - 1911; Fungi - 542; Plants - 1008; Viruses - 34; Other Eukaryotes - 606 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

30213705..30217102

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_106686.3 → NP_178153.1 Cyclin A2;4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_178153.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9C968

UniProtKB/TrEMBL

A0A178WID3, A0A5S9WW13, A0A7G2E790

Conserved Domains (2) summary

cd20506
Location:329 → 443

CYCLIN_AtCycA-like_rpt2; second cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins

cd20562
Location:190 → 325

CYCLIN_AtCycA_like_rpt1; first cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins