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    DPMS3 dolichol-phosphate mannosyltransferase-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841232, updated on 15-Feb-2024

    Summary

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    Gene symbol
    DPMS3
    Gene description
    dolichol-phosphate mannosyltransferase-like protein
    Primary source
    Araport:AT1G48140
    Locus tag
    AT1G48140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    dolichol phosphate mannose synthase 3; F21D18.14; F21D18_14
    Summary
    Encodes a subunit of the dolichol phosphate mannase synthase (DPMS) complex that may serve as membrane anchors for the catalytic core, DPMS1, or provide catalytic assistance. It is localized in the ER and mediates isoprenyl-linked glycan biogenesis.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (17781988..17784211)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein phosphatase 7 long form-like protein Neighboring gene 1-cysteine peroxiredoxin 1 Neighboring gene plant mobile domain protein Neighboring gene MADS-box transcription factor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis. Jadid N, et al. Plant Cell, 2011 May. PMID 21558543, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In plants, Dol-P-Man is synthesized when Dol-P-Man synthase1 (DPMS1), the catalytic core, interacts with two binding proteins, DPMS2 and DPMS3, that may serve as membrane anchors for DPMS1 or provide catalytic assistance.
      Title: DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001198239.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    contributes_to dolichyl-phosphate beta-D-mannosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of dolichol-phosphate-mannose synthase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    dolichol-phosphate mannosyltransferase-like protein
    NP_001185168.1
    • dolichol-phosphate mannosyltransferase-related; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dolichol-phosphate mannosyltransferase subunit 3 (InterPro:IPR013174).
    NP_564521.1
    • dolichol-phosphate mannosyltransferase-related; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Dolichol-phosphate mannosyltransferase subunit 3 (InterPro:IPR013174); Has 82 Blast hits to 81 proteins in 36 species: Archae - 0; Bacteria - 0; Metazoa - 30; Fungi - 13; Plants - 38; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17781988..17784211
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103710.3 → NP_564521.1  dolichol-phosphate mannosyltransferase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564521.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LEQ4, Q9LNG6
      UniProtKB/TrEMBL
      A0A178WDH1, A0A5S9WPU4
      Conserved Domains (1) summary
      pfam08285
      Location:1 → 84
      DPM3; Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)

    2. NM_001198239.1 → NP_001185168.1  dolichol-phosphate mannosyltransferase-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185168.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HWT0
      Conserved Domains (1) summary
      pfam08285
      Location:7 → 70
      DPM3; Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LEQ4.1

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