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    MEF3 Pentatricopeptide repeat (PPR) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837123, updated on 15-Feb-2024

    Summary

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    Gene symbol
    MEF3
    Gene description
    Pentatricopeptide repeat (PPR) superfamily protein
    Primary source
    Araport:AT1G06140
    Locus tag
    AT1G06140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    mitochondrial editing factor 3; T21E18.19; T21E18_19
    Summary
    Encodes MEF3 (mitochondrial editing factor 3), a PPR (pentatricopeptide repeat) protein of the E domain subclass. Functions in mitochondrial RNA editing.
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    Genomic context

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    See MEF3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (1864774..1866999)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene basic helix loop helix DNA-binding superfamily protein Neighboring gene basic helix loop helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The E-class PPR protein MEF3 of Arabidopsis thaliana can also function in mitochondrial RNA editing with an additional DYW domain. Verbitskiy D, et al. Plant Cell Physiol, 2012 Feb. PMID 22186180
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The nuclear gene MEF3 complements mitochondrial RNA editing defects at the atp4-89 site
      Title: The E-class PPR protein MEF3 of Arabidopsis thaliana can also function in mitochondrial RNA editing with an additional DYW domain.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_100495.2

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial mRNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Pentatricopeptide repeat (PPR) superfamily protein
    NP_172104.1
    • Pentatricopeptide repeat (PPR) superfamily protein; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G33990.1); Has 38916 Blast hits to 13813 proteins in 232 species: Archae - 0; Bacteria - 13; Metazoa - 106; Fungi - 93; Plants - 38173; Viruses - 0; Other Eukaryotes - 531 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1864774..1866999
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100495.2 → NP_172104.1  Pentatricopeptide repeat (PPR) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172104.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LND4
      UniProtKB/TrEMBL
      A0A178WDW8, A0A5S9SVP4, A0A654E767
      Conserved Domains (2) summary
      PLN03077
      Location:24 → 557
      PLN03077; Protein ECB2; Provisional
      sd00004
      Location:380 → 407
      PPR; PPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LND4.1

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