U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ERS2 ethylene response sensor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839549, updated on 7-Sep-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    ERS2
    Gene description
    ethylene response sensor 2
    Primary source
    Araport:AT1G04310
    Locus tag
    AT1G04310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ERS2 PROTEIN; ethylene response sensor 2; F19P19.25; F19P19_25
    Summary
    encodes an ethylene receptor related to bacterial two-component histidine kinases.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (1154740..1157813, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Thioesterase superfamily protein Neighboring gene ncRNA Neighboring gene TRAF-like superfamily protein Neighboring gene tRNA-Gly Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ethylene insensitivity conferred by Arabidopsis ERS gene. Hua J, et al. Science, 1995 Sep 22. PMID 7569898
    2. Subcellular localization and in vivo interactions of the Arabidopsis thaliana ethylene receptor family members. Grefen C, et al. Mol Plant, 2008 Mar. PMID 19825542
    3. Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis. Gao Z, et al. J Biol Chem, 2008 Aug 29. PMID 18577522, Free PMC Article
    4. New insight in ethylene signaling: autokinase activity of ETR1 modulates the interaction of receptors and EIN2. Bisson MM, et al. Mol Plant, 2010 Sep. PMID 20591837
    5. Ethylene-binding activity, gene expression levels, and receptor system output for ethylene receptor family members from Arabidopsis and tomato. O'Malley RC, et al. Plant J, 2005 Mar. PMID 15703053

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ETR1 and ERS2 can form disulfide-linked heterodimers.
      Title: Heteromeric interactions among ethylene receptors mediate signaling in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_100312.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ethylene binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables phosphorelay sensor kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein histidine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein serine/threonine kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ethylene response sensor 2
    NP_171927.1
    • ethylene response sensor 2 (ERS2); FUNCTIONS IN: ethylene binding, protein histidine kinase activity, receptor activity, glycogen synthase kinase 3 activity; INVOLVED IN: negative regulation of ethylene mediated signaling pathway; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661), GAF (InterPro:IPR003018); BEST Arabidopsis thaliana protein match is: Signal transduction histidine kinase, hybrid-type, ethylene sensor (TAIR:AT3G23150.1); Has 9957 Blast hits to 9833 proteins in 1310 species: Archae - 33; Bacteria - 8177; Metazoa - 2; Fungi - 375; Plants - 1006; Viruses - 0; Other Eukaryotes - 364 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1154740..1157813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331475.1 → NP_001323287.1  ethylene response sensor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0FVU3, B0FVU5, B0FVW8, B0FVX0, B0FVX9, P93825
      UniProtKB/TrEMBL
      A0A178WDB1, A0A5S9SJV6
      Conserved Domains (3) summary
      smart00065
      Location:190 → 356
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      PRK11466
      Location:359 → 506
      PRK11466; hybrid sensory histidine kinase TorS; Provisional
      cd16938
      Location:487 → 613
      HATPase_ETR2_ERS2-EIN4-like; Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains

    2. NM_100312.4 → NP_171927.1  ethylene response sensor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171927.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0FVU3, B0FVU5, B0FVW8, B0FVX0, B0FVX9, P93825
      UniProtKB/TrEMBL
      A0A178WDB1, A0A5S9SJV6
      Conserved Domains (3) summary
      smart00065
      Location:190 → 356
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      PRK11466
      Location:359 → 506
      PRK11466; hybrid sensory histidine kinase TorS; Provisional
      cd16938
      Location:487 → 613
      HATPase_ETR2_ERS2-EIN4-like; Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P93825.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools